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ChemicalBook CAS DataBase List 1-(4-FLUOROPHENYL)-3-(4-METHYLPHENYL)-1H-PYRAZOLE-4-CARBALDEHYDE
618098-56-9

1-(4-FLUOROPHENYL)-3-(4-METHYLPHENYL)-1H-PYRAZOLE-4-CARBALDEHYDE synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: acetic acid / methanol / 18 h / 20 °C / Inert atmosphere
2: trichlorophosphate / chloroform-d1 / 18 h / 70 °C / Inert atmosphere; Cooling with ice

References:

Yu, Donna D.;Lin, Wenwei;Forman, Barry M.;Chen, Taosheng [Bioorganic and Medicinal Chemistry,2014,vol. 22,# 11,p. 2919 - 2938]