6-METHYLAMINO-1,3-DIMETHYLURACIL synthesis
- Product Name:6-METHYLAMINO-1,3-DIMETHYLURACIL
- CAS Number:5770-42-3
- Molecular formula:C7H11N3O2
- Molecular Weight:169.18
Yield:5770-42-3 95%
Reaction Conditions:
in methanol; for 16 h;Large scale;
Steps:
2 (2) Preparation of 1,3-dimethyl-6-methylaminopyrimidine-2,4-dione (Preparation of compound SM3)
The compound SM2 (6.5 kg, 37.3mol) was dissolved in 50L methanol. Drop methylamine alcohol solution 50L, reaction 16 hours, HPLC monitoring, after the reaction, concentrated, and adding water (20L), the ethyl acetate extract (20L * 3), combined with the organic phase, saturated salt water washing (10L), anhydrous sodium sulfate drying, filtering, reduced pressure distillation to remove the organic phase, dried under vacuum to get white solid 6.0 kg, is fine compound SM3, yield: 95.0%.
References:
CN103755705,2017,B Location in patent:Paragraph 0033; 0037; 0038
6972-27-6
218 suppliers
$6.00/1g
4229-44-1
241 suppliers
$10.00/1g
5770-42-3
26 suppliers
inquiry
510773-30-5
0 suppliers
inquiry
6972-27-6
218 suppliers
$6.00/1g
5770-42-3
26 suppliers
inquiry