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ChemicalBook CAS DataBase List 6-CHLORO-2-IODO-3-HYDROXYPYRIDINE
188057-26-3

6-CHLORO-2-IODO-3-HYDROXYPYRIDINE synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: BF3*Et2O; i-BuONO / 1,2-dimethoxy-ethane; CH2Cl2 / 0 °C
1.2: 62 percent / 75 °C
2.1: 94 percent / K2CO3 / methanol / 20 °C
3.1: 95 percent / I2; Na2CO3 / H2O

References:

Mathes, Brian M.;Filla, Sandra A. [Tetrahedron Letters,2003,vol. 44,# 4,p. 725 - 728]

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