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ChemicalBook CAS DataBase List 6-BROMO-5-IODOPYRIDIN-3-AMINE
697300-68-8

6-BROMO-5-IODOPYRIDIN-3-AMINE synthesis

2synthesis methods
25391-58-6 Synthesis
2-HYDROXY-3-IODO-5-NITROPYRIDINE  97

25391-58-6
82 suppliers
$8.00/1g

-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 81.1 percent / POBr3 / toluene; quinoline / 90 - 100 °C
2: 74 percent / iron powder; aq. acetic acid / 70 - 72 °C

References:

Zhang, Yi;Pavlova, Olga A.;Chefer, Svetlana I.;Hall, Andrew W.;Kurian, Varughese;Brown, LaVerne L.;Kimes, Alane S.;Mukhin, Alexey G.;Horti, Andrew G. [Journal of Medicinal Chemistry,2004,vol. 47,# 10,p. 2453 - 2465]

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