午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 5-AMINO-1-(2,4-DICHLOROPHENYL)-3-METHYL-1H-PYRAZOLE-4-CARBONITRILE
58791-83-6

5-AMINO-1-(2,4-DICHLOROPHENYL)-3-METHYL-1H-PYRAZOLE-4-CARBONITRILE synthesis

1synthesis methods
5446-18-4 Synthesis
2,4-Dichlorophenylhydrazine hydrochloride

5446-18-4
274 suppliers
$13.00/1g

5417-82-3 Synthesis
(1-ETHOXYETHYLIDENE)MALONONITRILE

5417-82-3
119 suppliers
$9.00/1g

-

Yield:58791-83-6 73%

Reaction Conditions:

with sodium acetate in ethanol; for 1 h;Reflux;

Steps:

General Procedure for the synthesis of compounds 5-amino-1-aryl-3-methyl-1H-pyrazole-4-carbonitrile 2a-m.

General procedure: Arylhydrazine hydrochlorides (0.01mol) were reacted with (1-ethoxyethylidene)malononitrile (0.01 mol) and sodium acetate (0.02mol) in ethanol (40mL), under reflux, during 1h. After, the mixture was poured in cold water and the precipitate formed was filtered out and recrystallized from ethanol/water. The reactions were accomplished by means of TLC using silica gel plate with fluorescent indicator and hexane/ethyl acetate(1:1) as eluent.

References:

Faria, Jéssica V.;Dos Santos, Maurício S.;Bernardino, Alice M.R.;Becker, Klaus M.;Machado, Gérzia M.C.;Rodrigues, Raquel F.;Canto-Cavalheiro, Marilene M.;Leon, Leonor L. [Bioorganic and Medicinal Chemistry Letters,2013,vol. 23,# 23,p. 6310 - 6312] Location in patent:supporting information

5-AMINO-1-(2,4-DICHLOROPHENYL)-3-METHYL-1H-PYRAZOLE-4-CARBONITRILE Related Search: