午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

1174906-84-3

5-CHLORO-2-METHYLTHIOBENZAMIDE synthesis

1synthesis methods
5-chloro-2-MethylbenzaMide

1028252-11-0
14 suppliers
inquiry

5-CHLORO-2-METHYLTHIOBENZAMIDE

1174906-84-3
8 suppliers
$60.00/1g

-

Yield:-

Reaction Conditions:

with Lawessons reagent in tetrahydrofuran at 23; for 1 h;

Steps:

4.2. Preparation of thioamides 2. General procedure

General procedure: Amides (1 mmol) and Lawesson's reagent (490 mg, 1.2 mmol) were added to dry THF (15 mL). The reaction mixture was stirred at room temperature for 1 h, or heated under reflux for 5 h in the case of the 4-nitro derivative. The solvent was evaporated under reduced pressure and the residue was partitioned between aq NaHCO3 (25 mL) and ethyl acetate (25 mL). The organic solvent was separated and dried over anhydrous MgSO4. The crude product was further purified by silica gel flash chromatography, using hexane-ethyl acetate (4:1), to yield the corresponding thioamides as yellow solids (42-60%). 4-Nitrothioamide (2ff),38 4-cyanothiobenzamide (2gg)39 and 3-cyanothiobenzamide (2hh),40 3-methoxythiobenzamide (2ii)41 have been previously reported.

References:

Mayhoub, Abdelrahman S.;Marler, Laura;Kondratyuk, Tamara P.;Park, Eun-Jung;Pezzuto, John M.;Cushman, Mark [Bioorganic and Medicinal Chemistry,2012,vol. 20,# 1,p. 510 - 520] Location in patent:experimental part