4H-Pyran-4-one, 2,3-dihydro-5-hydroxy-6-methyl- synthesis
- Product Name:4H-Pyran-4-one, 2,3-dihydro-5-hydroxy-6-methyl-
- CAS Number:38877-21-3
- Molecular formula:C6H8O3
- Molecular Weight:128
53951-42-1
1 suppliers
inquiry
38877-21-3
6 suppliers
inquiry
Yield:38877-21-3 24%
Reaction Conditions:
with sodium hydrogensulfite;potassium bromide in dichloromethane;water;acetonitrile at 20; for 4 h;
Steps:
3 Example 3 Synthesis of Dihydromaltol (IV)
500ml three bottle, electromagnetic stirring, water bath. Add a mixture of acetonitrile, dichloromethane and water 180ml (1:1:1)With 5 g of 2-methyl-3,4-dihydroxy-tetrahydropyran, potassium bromide, sodium bisulfite 4.8 g and 3.6 g were added thereto with stirring. Stir at room temperature for 4 hours. 200 ml of water was added and stirred for 10 minutes. The aqueous phase was extracted 3 times with chloroform; the organic phases were combined and concentrated. Under reduced pressure, a 75-76°C/700 kPa fraction was collected, 1.17 g (24% yield).
References:
CN104370868,2017,B Location in patent:Paragraph 0027; 0028; 0029; 0030
504-60-9
93 suppliers
$180.00/1ml
38877-21-3
6 suppliers
inquiry