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41042-21-1

2,3-dihydro-2,3-dioxo-1h-indole-1-aceticaciethylester synthesis

6synthesis methods
-

Yield:41042-21-1 100%

Reaction Conditions:

Stage #1: indole-2,3-dionewith calcium hydride in N,N-dimethyl-formamide at 100; for 1 h;
Stage #2: ethyl bromoacetate in N,N-dimethyl-formamide at 100; for 4 h;

References:

L?tter, Angelique N.C.;Pathak, Rakhi;Sello, Thato S.;Fernandes, Manuel A.;van?Otterlo, Willem A.L.;de Koning, Charles B. [Tetrahedron,2007,vol. 63,# 10,p. 2263 - 2274]