4-IODO-3-NITROTOLUENE synthesis
- Product Name:4-IODO-3-NITROTOLUENE
- CAS Number:5326-39-6
- Molecular formula:C7H6INO2
- Molecular Weight:263.03
27329-27-7
103 suppliers
$7.00/250mg
5326-39-6
156 suppliers
$6.00/1g
Yield:5326-39-6 53%
Reaction Conditions:
with 2.9-dimethyl-1,10-phenanthroline;oxygen;copper (I) acetate;silver sulfate;sodium iodide in dimethyl sulfoxide at 160; for 24 h;Schlenk technique;
Steps:
18 Example 18. Synthesis of 2-nitro-4-methyl iodobenzene.
Silak reaction tube equipped with a magnetic stirrer was charged with 6.2 mg of silver sulfate,21.8 mg of copper acetate, 12.5 mg of 2,9-dimethyl-1,10-o-phenanthroline,36.2 mg of 2-nitro-4-methylbenzoic acid and 45 mg of sodium iodide4 mL of dimethyl sulfoxide. Heat 160 ° C in the presence of oxygenReaction for 24 hours. After the reaction was completed, distilled water was added to quench the reaction,Extraction with ethyl acetate 3 times, each time 10mL,The combined organic phases were concentrated to give 27.9 mg of 2-nitro-4-methyliodobenzene,The yield is 53%.
References:
Nanchang University;Fu Zhengjiang;Cai Hu;Li Zhaojie;Jiang Ligao CN107325002, 2017, A Location in patent:Paragraph 0091
89-62-3
229 suppliers
$13.00/25g
5326-39-6
156 suppliers
$6.00/1g
624-31-7
437 suppliers
$9.00/25g
99-99-0
324 suppliers
$5.00/5 g
5326-39-6
156 suppliers
$6.00/1g
41252-97-5
185 suppliers
$6.00/1g