4-HYDROXY-3-METHYLPHENYL THIOCYANATE synthesis
- Product Name:4-HYDROXY-3-METHYLPHENYL THIOCYANATE
- CAS Number:3774-53-6
- Molecular formula:C8H7NOS
- Molecular Weight:165.21
333-20-0
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$13.50/100G
95-48-7
442 suppliers
$18.00/25g
3774-53-6
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$59.00/500mg
Yield:3774-53-6 93%
Reaction Conditions:
with 1,2-diphenyl-1,1,2,2-tetrahydroperoxyethane;acetic acid in water at 20; for 0.166667 h;
Steps:
General procedure for thiocyanation of phenols and anilines derivatives
General procedure: To a mixture of aromatic substrate (1 mmol), THPDPE (1mmol) and HOAc (0.1 mmol) in H2O (4 mL), KSCN (1 mmol) was added and the solution was stirred at room temperature for appropriate time and monitored by TLC. After completion of the reaction, the mixture was quenched with Na2SO3 (1 M, 3 mL) and extracted by CHCl3 (3×5 mL). After evaporation of the solvent, the residue was recrystallized and purified using chromatography. All of the products were characterized on the basis of their melting points, IR, 1H NMR, and 13C NMR spectral analysis and compared with those reported
References:
Khosravi, Kaveh;Naserifar, Shirin [Tetrahedron,2018,vol. 74,# 45,p. 6584 - 6592] Location in patent:supporting information
540-72-7
446 suppliers
$13.50/100G
95-48-7
442 suppliers
$18.00/25g
3774-53-6
66 suppliers
$59.00/500mg
95-48-7
442 suppliers
$18.00/25g
3774-53-6
66 suppliers
$59.00/500mg