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ChemicalBook CAS DataBase List 4(4'-trifluoroMethylphenyl)butanoic acid
136295-01-7

4(4'-trifluoroMethylphenyl)butanoic acid synthesis

2synthesis methods
128796-39-4 Synthesis
4-Trifluoromethylphenylboronic acid

128796-39-4
434 suppliers
$10.00/5g

4(4'-trifluoroMethylphenyl)butanoic acid

136295-01-7
25 suppliers
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Yield:136295-01-7 73%

Reaction Conditions:

with manganese(I) pentacarbonyl bromide;lithium hydroxide monohydrate;potassium hydroxide in 1,3-dimethylbenzene at 20; for 24 h;Inert atmosphere;regioselective reaction;

References:

Han, Jingqiang;Yu, Huimin;Zi, Weiwei [Organic Letters,2022,vol. 24,# 33,p. 6154 - 6158] Location in patent:supporting information