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883194-93-2

4-(4-NITRO-PHENYL)-PIPERIDINE HYDROCHLORIDE synthesis

1synthesis methods
2,2,2-trifluoro-1-(4-(4-nitrophenyl)piperidin-1-yl)ethanone

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4-(4-NITRO-PHENYL)-PIPERIDINE HYDROCHLORIDE

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Yield:-

Reaction Conditions:

Stage #1: 2,2,2-trifluoro-1-[4-(4-nitro-phenyl)-piperidin-1-yl]-ethanonewith methanol;potassium carbonate at 20; for 48 h;
Stage #2: with hydrogenchloride in water;

References:

WO2006/40279,2006,A1 Location in patent:Page/Page column 118