4,4'-Biphenol synthesis
- Product Name:4,4'-Biphenol
- CAS Number:92-88-6
- Molecular formula:C12H10O2
- Molecular Weight:186.21
4,4′-Biphenol is synthesised by dealkylation of the tetra-t-butyl derivative, generated by the oxidative coupling of 2,6-di-tert-butylphenol.
![3,3',5,5'-TETRA(TERT-BUTYL)[1,1'-BIPHENYL]-4,4'-DIOL](/CAS/GIF/128-38-1.gif)
128-38-1
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92-88-6
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115-11-7
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Yield:92-88-6 99%
Reaction Conditions:
with methanesulfonic acid in isopar-G (hydrocarbons C10-C11);toluene at 150; for 2 h;
Steps:
7 Example 7
In a three-necked flask 50 grams [OF 2, 2', 6, 6'-TETRA-T-BUTYL-4, 4'-BIPHENOL (N] and 0.25 gm of [METHANESULFONIC] acid were mixed with a mixture of 80 ml Isopar-G (hydrocarbons [C10-C11)] and 20 ml of toluene. After 2 hours at [150°C,] 26 grams of isobutylene is collected in a dry ice trap and the reaction cooled to room temperature and was filtered. The biphenol was dried at [130°C,] giving 22.5 gram of 4, 4'-biphenol (99% yield) with purity >99% were collected.
References:
WO2004/18401,2004,A1 Location in patent:Page 10
92-52-4
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2132-80-1
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92-88-6
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540-38-5
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92-88-6
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