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ChemicalBook CAS DataBase List 3-Pyridinepropanol,6-fluoro-(9CI)
174523-84-3

3-Pyridinepropanol,6-fluoro-(9CI) synthesis

1synthesis methods
766-11-0 Synthesis
5-Bromo-2-fluoropyridine

766-11-0
453 suppliers
$6.00/5g

3-Pyridinepropanol,6-fluoro-(9CI)

174523-84-3
1 suppliers
inquiry

-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / 16 h / 90 °C / Inert atmosphere
2: hydrogen; palladium on activated charcoal / methanol / 16 h / 20 °C

References:

Bernard-Gauthier, Vadim;Mossine, Andrew V.;Knight, Ashley;Patnaik, Debasis;Zhao, Wen-Ning;Cheng, Chialin;Krishnan, Hema S.;Xuan, Lucius L.;Chindavong, Peter S.;Reis, Surya A.;Chen, Jinshan Michael;Shao, Xia;Stauff, Jenelle;Arteaga, Janna;Sherman, Phillip;Salem, Nicolas;Bonsall, David;Amaral, Brenda;Varlow, Cassis;Wells, Lisa;Martarello, Laurent;Patel, Shil;Liang, Steven H.;Kurumbail, Ravi G.;Haggarty, Stephen J.;Scott, Peter J. H.;Vasdev, Neil [Journal of Medicinal Chemistry,2019,vol. 62,# 21,p. 9600 - 9617]