ChemicalBook CAS DataBase List ethyl cyclopent-3-ene-1-carboxylate

ethyl cyclopent-3-ene-1-carboxylate synthesis

9synthesis methods

Product Name:ethyl cyclopent-3-ene-1-carboxylate
CAS Number:21622-01-5
Molecular formula:C8H12O2
Molecular Weight:140.18

64-17-5 Synthesis

64-17-5
729 suppliers
$10.00/50g

7686-77-3 Synthesis

7686-77-3
270 suppliers
$6.00/1g

21622-01-5
110 suppliers
$50.00/1 g

Yield: 89.42%

Reaction Conditions:

with thionyl chloride at 5 - 20; for 1.5 h;

Steps:

1
Example 1 Preparation of ethyl-3-cyclopentene-1-carboxylate (5) A solution of 3-cyclopentene-1-carboxylic acid (500 g, 4.45 mole) in ethanol (500 mL) was stirred at 5-10° C. Then thionyl chloride (257.59 g, 2.16 mole) was added in a drop wise manner for 1 hr. After complete addition was over, the reaction mixture was stirred at room temperature for 30 min. The reaction mixture was poured into the water (1000 mL) and extracted with ethyl acetate (2*250 mL). The ethyl acetate layer was washed with 10% sodium carbonate solution (500 mL), with water (2*500 mL) and concentrated to give ethyl-3-cyclopentene-1-carboxylate (5). Yield: 558 g, 89.42%.

References:

Tarur, Venkatasubramanian Radhakrishnan;Sathe, Dhananjay Govind;Bhise, Nandu Baban;Sawant, Kamlesh Digambar;Naik, Tushar Anil;Srivastav, Neeraj;Deore, Raviraj Bhatu US2008/275241, 2008, A1 Location in patent:Page/Page column 10