ChemicalBook CAS DataBase List 3-AMINO-6-PHENYLPYRIDAZINE

3-AMINO-6-PHENYLPYRIDAZINE synthesis

9synthesis methods

Product Name:3-AMINO-6-PHENYLPYRIDAZINE
CAS Number:14966-91-7
Molecular formula:C10H9N3
Molecular Weight:171.2

5469-69-2 Synthesis

5469-69-2
377 suppliers
$6.00/10g

98-80-6 Synthesis

98-80-6
740 suppliers
$5.00/5g

14966-91-7
65 suppliers
$52.00/100 mg

Yield: 79%

Reaction Conditions:

with tetrakis(triphenylphosphine) palladium⁽⁰⁾;potassium carbonate in 1,4-dioxane;water;toluene for 12 h;Reflux;

Steps:

11-3; 6
General procedure: phenylboronic acid (8.9 g, 0.073 mol), 4-bromo-2-naphthylamine (13.5 g, 0.061 mol), tetrakis(triphenylphosphine)palladium (3.62 g, 0.003 mol), potassium carbonate (25.3) g, 0.183 mol) was added to 75 mL of 1,4-dioxane, 75 mL of toluene, and 30 mL of distilled water, and refluxed for 12 hours.After cooling to room temperature, extraction with ethyl acetate, and separation by column chromatography to give [Intermediate 1-c] 10 g (75% yield).

References:

SFC Ltd.;Cha Sun-uk;Jeong Gyeong-seok;Park Seok-bae;Kim Hui-dae;Lee Yu-rim;Song Ju-man;Hwang Mun-chan KR102193832, 2020, B1 Location in patent:Paragraph 0198; 0207-0210; 0320-0324

88497-27-2 Synthesis