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ChemicalBook CAS DataBase List 3,5-Difluoromandelic acid
132741-31-2

3,5-Difluoromandelic acid synthesis

1synthesis methods
32085-88-4 Synthesis
3,5-Difluorobenzaldehyde

32085-88-4
263 suppliers
$19.00/25g

-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: sodium hydrogensulfite; water / diethyl ether / 2 h / 20 °C
1.2: 20 °C
2.1: water; hydrogenchloride / 1,4-dioxane / 6 h / Reflux

References:

Chen, Peiran;Yang, Wenhong [Tetrahedron Letters,2014,vol. 55,# 14,p. 2290 - 2294]

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