ChemicalBook CAS DataBase List 3',5'-Dichloroacetophenone

3',5'-Dichloroacetophenone synthesis

9synthesis methods

Product Name:3',5'-Dichloroacetophenone
CAS Number:14401-72-0
Molecular formula:C8H6Cl2O
Molecular Weight:189.04

3032-81-3
214 suppliers
$10.00/1g

108-24-7
5 suppliers
$14.00/250ML

14401-72-0
144 suppliers
$9.00/1g

Yield: 8 g

Reaction Conditions:

with tris-(dibenzylideneacetone)dipalladium⁽⁰⁾;N-ethyl-N,N-diisopropylamine;lithium chloride in N,N-dimethyl-formamide at 100; for 8 h;

Steps:

4.1
Dichloroiodobenzene(37. 0g, 136mmol), Pd ₂ (dba) ₃ (1. 5g, 1. 6mmol), lithium chloride (29. 0g, 682mmol) to, dissolved in 100 ml of DMF in 500 ml of a round bottom flask. 64. 0 ml of acetic anhydride and 47. 0 ml of N-ethyl diisopropylamide are then added to the reaction mixture. 8 100 °C the reaction product is heated. Water is added to the reaction mixture, product is extracted with ethyl acetate, ethyl acetate and eluent Phenylbicyclohexane using a immunochromatography glycopeptide is used. Obtd. 8g of the product.

References:

UNIVERSAL DISPLAY CORPORATION;ALLEYNE, BERT;KWONG, RAYMOND;YEAGER, WALTER;XIA, CHUANJUN JP2015/212297, 2015, A Location in patent:Paragraph 0106; 0107

6575-00-4 Synthesis