3,4-Dimethoxy-2-Methylpyridine synthesis
- Product Name:3,4-Dimethoxy-2-Methylpyridine
- CAS Number:107512-35-6
- Molecular formula:C8H11NO2
- Molecular Weight:153.18
17184-19-9
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77-78-1
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107512-35-6
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$40.00/100mg
Yield: 44 g
Reaction Conditions:
with potassium hydroxide in water at 10 - 20; for 20 h;
Steps:
5 Example 5: Preparation of 3,4-dimethoxy-2-methylpyridine.
38 g of 3-hydroxy-2-methyl-4-pyridone was added to the reaction flask, 90 g of water, and 35 g of potassium hydroxide were stirred and dissolved.Add 75g of dimethyl sulfate at 10~20°C, and keep warm for 20h.After adding 80 g of dichloromethane and stirring for 15 minutes, the layers were separated, and the aqueous layer was stirred with 20 g of dichloromethane for 15 minutes and then layered.The methylene chloride layers were combined and evaporated under reduced pressure to dryness to give 44 g of 3,4-dimethoxy-2-methylpyridine.
References:
Shouguang Fukang Pharmaceutical Co., Ltd.;Dong Liangjun;Sun Jiguo;Liu Jie;Guo Jianhui;Jia Zongqing;Yang Dawei;Wang Haipeng;Wang Hongming;Hou Junjie CN104557692, 2018, B Location in patent:Paragraph 0030; 0031
107512-34-5
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107512-35-6
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$40.00/100mg
109613-93-6
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$62.00/100mg
74-88-4
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$15.00/10g
107512-35-6
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$40.00/100mg
118-71-8
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$5.00/25mg
107512-35-6
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$40.00/100mg
620-08-6
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$5.00/1g
107512-35-6
52 suppliers
$40.00/100mg