3-(1H-INDOL-1-YL)PROPAN-1-AMINE HYDROCHLORIDE synthesis
- Product Name:3-(1H-INDOL-1-YL)PROPAN-1-AMINE HYDROCHLORIDE
- CAS Number:46170-17-6
- Molecular formula:C11H14N2
- Molecular Weight:174.24
Yield:46170-17-6 59%
Reaction Conditions:
Stage #1: indolewith sodium hydride in N,N-dimethyl-formamide at 0; for 0.5 h;
Stage #2: 3-chloropropylamine hydrochloride in N,N-dimethyl-formamide at 0; for 2 h;
References:
Woodring, Jennifer L.;Lu, Shao-Hung;Krasnova, Larissa;Wang, Shih-Chi;Chen, Jhih-Bin;Chou, Chiu-Chun;Huang, Yi-Chou;Cheng, Ting-Jen Rachel;Wu, Ying-Ta;Chen, Yu-Hou;Fang, Jim-Min;Tsai, Ming-Daw;Wong, Chi-Huey [Journal of Medicinal Chemistry,2020,vol. 63,# 1,p. 205 - 215] Location in patent:supporting information
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