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ChemicalBook CAS DataBase List 3-Pyrrolidinol, 5-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, (3R,5S)-
260417-94-5

3-Pyrrolidinol, 5-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, (3R,5S)- synthesis

5synthesis methods
1-Pyrrolidinecarboxylic acid, 2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-4-hydroxy-, phenylmethyl ester, (2S,4R)-

260417-93-4
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3-Pyrrolidinol, 5-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, (3R,5S)-

260417-94-5
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Yield:260417-94-5 100%

Reaction Conditions:

with hydrogen;palladium on activated charcoal in ethanol;Hydrogenolysis;

References:

Gregson, Stephen J.;Howard, Philip W.;Corcoran, Kathryn E.;Barcella, Simona;Yasin, Maqsood M.;Hurst, Abigail A.;Jenkins, Terence C.;Kelland, Lloyd R.;Thurston, David E. [Bioorganic and Medicinal Chemistry Letters,2000,vol. 10,# 16,p. 1845 - 1847]