午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List Imidazo[1,2-a]pyridine-2-carboxaldehyde, 6-methyl- (9CI)
202348-55-8

Imidazo[1,2-a]pyridine-2-carboxaldehyde, 6-methyl- (9CI) synthesis

1synthesis methods
-

Yield:-

Reaction Conditions:

with manganese(IV) oxide in dichloromethane at 20; for 92.5 h;Heating / reflux;

Steps:

334.c

Step (c) 6-Methylimidazo[l,2-a]pyridine-2-carbaldehydeTo a solution of (6-methylimidazo[l,2-a]pyridin-2-yl)methanol (0.84 g, 5.18 mmol) in DCM (15 ml) was added manganese dioxide (0.450 g, 5.18 mmol) and the reaction mixture was stirred under nitrogen at ambient temperature for 1.5 h and left to stand for a further 18 h. The reaction mixture was heated to reflux for 3 h before further manganese dioxide (2.5 g, 28.76 mmol) and DCM (15.00 ml) was added. The reaction mixture was stirred at reflux for 3 Ii and left to stand at room temperature for 67 h. The mixture was filtered through a pad of celite, washing with DCM. The filtrate was concentrated, triturated with ether and filtered to give the sub title compound as a beige solid (0.283 g). 1H NMR (400 MHz, CDCl3) δ 10.13 (s, IH), 8.07 (s, IH), 7.94 (d, J = 1.3 Hz, IH), 7.58 (d, J = 9.5 Hz, IH), 7.14 (dd, J = 9.5, 1.5 Hz, IH), 2.38 (s, 3H). [M+H]=161

References:

WO2008/84223,2008,A2 Location in patent:Page/Page column 424-425

Imidazo[1,2-a]pyridine-2-carboxaldehyde, 6-methyl- (9CI) Related Search: