![2819-56-9](/CAS/GIF/2819-56-9.gif)
2-OXO-1-OXA-SPIRO[4.5]DECANE-4-CARBOXYLIC ACID synthesis
- Product Name:2-OXO-1-OXA-SPIRO[4.5]DECANE-4-CARBOXYLIC ACID
- CAS Number:2819-56-9
- Molecular formula:C10H14O4
- Molecular Weight:198.22
![ethyl 2-oxo-1-oxaspiro[4.5]decane-4-carboxylate](/CAS/20180703/GIF/61858-03-5.gif)
61858-03-5
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![2-OXO-1-OXA-SPIRO[4.5]DECANE-4-CARBOXYLIC ACID](/CAS/GIF/2819-56-9.gif)
2819-56-9
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$31.00/200μmol
Yield:2819-56-9 91%
Reaction Conditions:
with water;lithium hydroxide in tetrahydrofuran at 20; for 4 h;
Steps:
1
The obtained product V-7 was added to a mixed solution of tetrahydrofuran and water (v/v = 3/1), 2 equivalents of lithium hydroxide solid was added, and the mixture was reacted at room temperature for 4 hours.After completion of the reaction, the reaction mixture was acidified with a 1N aqueous solution of hydrochloric acid, ethyl acetate, and concentrated under reduced pressure to afford product IV-7, yield 91%.
References:
CN108530407,2018,A Location in patent:Paragraph 0043; 0045; 0047
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![2-OXO-1-OXA-SPIRO[4.5]DECANE-4-CARBOXYLIC ACID](/CAS/GIF/2819-56-9.gif)
2819-56-9
17 suppliers
$31.00/200μmol
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![2-OXO-1-OXA-SPIRO[4.5]DECANE-4-CARBOXYLIC ACID](/CAS/GIF/2819-56-9.gif)
2819-56-9
17 suppliers
$31.00/200μmol
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134515-27-8
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![2-OXO-1-OXA-SPIRO[4.5]DECANE-4-CARBOXYLIC ACID](/CAS/GIF/2819-56-9.gif)
2819-56-9
17 suppliers
$31.00/200μmol
![Cyclohexanone](/CAS/GIF/108-94-1.gif)
108-94-1
546 suppliers
$12.00/50g
![2-OXO-1-OXA-SPIRO[4.5]DECANE-4-CARBOXYLIC ACID](/CAS/GIF/2819-56-9.gif)
2819-56-9
17 suppliers
$31.00/200μmol