2-(DODECYLOXY)ETHANOL synthesis
- Product Name:2-(DODECYLOXY)ETHANOL
- CAS Number:4536-30-5
- Molecular formula:C14H30O2
- Molecular Weight:230.39
107-21-1
1358 suppliers
$10.00/25g
143-15-7
456 suppliers
$5.00/25g
4536-30-5
58 suppliers
$186.00/1ml
Yield:4536-30-5 69%
Reaction Conditions:
with tetrabutylammomium bromide;potassium hydroxide in 1,4-dioxane at 100 - 105;
Steps:
Ethylene glycol and diethylene glycol monoalkyl ethers 8a-e (general procedure).
General procedure: Dioxane (15 mL), alkyl halide (25 mmol), and tetrabutylammonium bromide (0.4 g, 1.2 mmol) were added to a solution of KOH (1.6 g, 27.5 mmol) in glycol (75-125 mmol). After stirring at 100-105 °C for 5-10 h, the reaction mixture was diluted with CHCl3 (15 mL) and water (10 mL). The organic layer was separated, washed with water (3×20 mL), dried with Na2SO4, and evaporated in vacuo, and the residue was distilled using Vigreux column. For each particular case, the ratio of the starting reagents, yields, physicochemical parameters, and 1H NMR spectral data for monoalkyl ethers 8a-e are givenin Table 6.
References:
Kharlamov;Artyushin;Bondarenko [Russian Chemical Bulletin,2014,vol. 63,# 11,p. 2445 - 2454][Izv. Akad. Nauk, Ser. Khim.,2014,# 11,p. 2445 - 2454]
4292-19-7
152 suppliers
$18.00/1g
107-21-1
1358 suppliers
$10.00/25g
4536-30-5
58 suppliers
$186.00/1ml
96-49-1
510 suppliers
$6.00/100g
112-53-8
457 suppliers
$10.00/5g
4536-30-5
58 suppliers
$186.00/1ml
112-41-4
238 suppliers
$8.00/10g
107-21-1
1358 suppliers
$10.00/25g
4536-30-5
58 suppliers
$186.00/1ml
112-41-4
238 suppliers
$8.00/10g
107-21-1
1358 suppliers
$10.00/25g
4536-30-5
58 suppliers
$186.00/1ml
22870-18-4
4 suppliers
$57.00/250mg