ChemicalBook CAS DataBase List 2-CHLORO-4,6-DIAMINO-1,3,5-TRIAZINE

2-CHLORO-4,6-DIAMINO-1,3,5-TRIAZINE synthesis

6synthesis methods

Product Name:2-CHLORO-4,6-DIAMINO-1,3,5-TRIAZINE
CAS Number:3397-62-4
Molecular formula:C3H4ClN5
Molecular Weight:145.55

108-77-0
404 suppliers
$13.00/25g

3397-62-4
160 suppliers
$22.00/1g

Yield:3397-62-4 96%

Reaction Conditions:

with ammonium hydroxide in 1,2-dichloro-ethane at 3 - 42; for 6 h;Temperature;Solvent;

Steps:

3.1
1) Under stirring, 30 g of cyanuric chloride is dissolved in 160 g of 1,2-dichloroethane at 3 ° C, 60 g of 25% industrial ammonia water is added dropwise; the temperature is raised to 42 ° C, and the reaction is carried out for 6 h to obtain a reaction liquid. Under the same temperature conditions, after separating 1,2-dichloroethane by vacuum distillation, adding 180 g of purified water, stirring for 1 hour, then dropping to 25 ° C, suction filtration, washing with water, drying at 52 ° C for 7 h under vacuum to obtain 22.8 g intermediate(2-Chloro-4.6-diamino-1.3.5-triazine dry product),The mass yield of the intermediate is 96%

References:

Henan Houyi Pharmaceutical Co., Ltd.;Zhang Huagang;Wan Yi;Li Guixin CN108084102, 2018, A Location in patent:Paragraph 0032; 0036; 0038; 0040

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