2-BROMO-5-CHLORO-3-FLUORO-4-IODOPYRIDINE synthesis
- Product Name:2-BROMO-5-CHLORO-3-FLUORO-4-IODOPYRIDINE
- CAS Number:514798-05-1
- Molecular formula:C5HBrClFIN
- Molecular Weight:336.33
514797-97-8
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Yield:514798-05-1 76%
Reaction Conditions:
Stage #1: 2-bromo-5-chloro-3-fluoro-pyridinewith n-butyllithium;diisopropylamine in tetrahydrofuran;hexane at -75; for 2 h;
Stage #2: with iodine in tetrahydrofuran;hexane at -75; for 1 h;
References:
Schlosser, Manfred;Bobbio, Carla [European Journal of Organic Chemistry,2002,# 24,p. 4174 - 4180]
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