ChemicalBook CAS DataBase List [2,5]-DIBENZO-21-CROWN-7

[2,5]-DIBENZO-21-CROWN-7 synthesis

6synthesis methods

Product Name:[2,5]-DIBENZO-21-CROWN-7
CAS Number:14098-41-0
Molecular formula:C22H28O7
Molecular Weight:404.45

23116-94-1 Synthesis

23116-94-1
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112-26-5 Synthesis

112-26-5
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14098-41-0
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$45.00/500 mg

Yield:14098-41-0 54%

Reaction Conditions:

with diacetoxydibenzo-18-crown-6 in acetonitrile at 85; for 36 h;

Steps:

dibenzo-18-crown-6 (7)
General procedure: A suspension of 4 (1.0g, 3.45mmol) and K₂CO₃ (0.47g, 3.45 mmol) in acetonitrile (20mL) was heated to 85^oC. bis(2-chloroethyl) ether (0.49 g, 3.45 mmol) in acetonitrile (2.0 mL) was added dropwise over 3 h. The mixture was heated at 85^oC for 36 h, cooled,and acetonitrile was removed in vacuum. The residue was acidified with dil. HCl (0.45M, 200 mL). The aqueous layer was extracted with chloroform (2×20 mL). The chloroformlayer was dried over Na₂SO4 and the solvent evaporated in vacuum to give an oily compound which was purified by column chromatography on silica gel using ethyl acetate: pet ether (2:8 v/v) (7)

References:

Utekar, Druman R.;Samant, Shriniwas D. [Journal of the Korean Chemical Society,2014,vol. 58,# 2,p. 193 - 197]

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34604-52-9 Synthesis