2',4'-dihydroxybutyrophenone synthesis
- Product Name:2',4'-dihydroxybutyrophenone
- CAS Number:4390-92-5
- Molecular formula:C10H12O3
- Molecular Weight:180.2
107-92-6
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108-46-3
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4390-92-5
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$38.00/100mg
Yield: 99%
Reaction Conditions:
with boron trifluoride diethyl etherate in chlorobenzene at 80;Friedel-Crafts Acylation;
Steps:
2.3.1. General method for the synthesis of the precursor ketones
General procedure: A mixture of the appropriate carboxylic acid (5.44 mmol) and resorcinol (1.36 mmol) in C6H5Cl (0.6 mL) was treated with BF3.Et2O (5.44 mmol). The reaction was stirred at 80 °C until complete consumption of resorcinol was assessed by TLC. The reaction mixture was treated with brine (10 mL) and the products were extracted with EtOAc (3 × 10 mL). The organic layers were combined, dried over MgSO4 and concentrated under reduced pressure. The residues were purified by column chromatography, eluting with mixtures of hexanes and EtOAc
References:
Cortés, Iván;di Liberto, Melina G.;Kaufman, Teodoro S.;Derita, Marcos G.;Bracca, Andrea B.J. [Food Chemistry,2020,vol. 321,art. no. 126701]
4346-18-3
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108-46-3
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$10.00/10g
4390-92-5
85 suppliers
$38.00/100mg
106-31-0
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108-46-3
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$10.00/10g
4390-92-5
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$38.00/100mg
141-75-3
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108-46-3
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4390-92-5
85 suppliers
$38.00/100mg
![Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-](/CAS/20210305/GIF/1000210-73-0.gif)
1000210-73-0
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4390-92-5
85 suppliers
$38.00/100mg
1000210-73-0
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