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ChemicalBook CAS DataBase List 2,4-Dihydroxybenzoic acid
89-86-1

2,4-Dihydroxybenzoic acid synthesis

14synthesis methods
Prepared from resorcinol and potassium bicarbonate in glycerol or water by heating and passing carbon dioxide through the mixture.
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Yield:89-86-1 96.7%

Reaction Conditions:

with hydrogenchloride;CO2;potassium carbonate in water

Steps:

3 Example 3
Example 3 92.5g (0.84 mole) of resorcinol and 200.2 g (1.45 mole) of potassium carbonate are added to the filtrate obtained in Example 2 and reacted together at 95-105°C, for 2 hours maintaining 5 atm of CO2. The reaction mixtures are filtered at this temperatures, the filtered precipitates are dissolved in 380 g of water, and neutralized by 180 g of concentrated HCl. The white solid thus obtained is 125.2 g (0.81 mole, yield 96.7%) of 2,4-dihydroxybenzoic acid, having a melting point of from 224 to 226°c.

References:

Kolon Industries Inc. EP436379, 1991, A2

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