2,4-Dichloroquinazoline synthesis
- Product Name:2,4-Dichloroquinazoline
- CAS Number:607-68-1
- Molecular formula:C8H4Cl2N2
- Molecular Weight:199.04
86-96-4
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$22.00/25g
607-68-1
314 suppliers
$10.00/1g
Yield:607-68-1 99%
Reaction Conditions:
with trichlorophosphate for 2.5 h;Heating / reflux;
Steps:
1.A.1
As depicted above, 2,4(1 H, 3H)- quinazolinedione (2Og, 123.3 mmol) was dissolved in 315ml OfPOCl3 and heated to reflux for 2.5 hours. After cooling to room temperature, the mixture was concentrated in vacuo to remove excess POCl3, poured into saturated aqueous NaHCO3, and extracted with dichloromethane. The product was isolated from the extract 24.3 g (99%)
References:
ANGION BIOMEDICA CORPORATION WO2007/81978, 2007, A2 Location in patent:Page/Page column 67
86-96-4
251 suppliers
$22.00/25g
607-68-1
314 suppliers
$10.00/1g
32315-10-9
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$10.00/1g
1885-29-6
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$5.00/1g
607-68-1
314 suppliers
$10.00/1g
607-69-2
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$37.00/100mg
607-68-1
314 suppliers
$10.00/1g