2,3,4,6-TETRAFLUOROBENZENEBORONIC ACID synthesis
- Product Name:2,3,4,6-TETRAFLUOROBENZENEBORONIC ACID
- CAS Number:511295-00-4
- Molecular formula:C6H3BF4O2
- Molecular Weight:193.89
121-43-7
356 suppliers
$14.00/25mL
2367-82-0
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$24.00/1g
511295-00-4
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$29.39/250mg
Yield:511295-00-4 73%
Reaction Conditions:
with n-butyllithium in diethyl ether;hexane;n-BuLi (2.5 M in hexane) was dropped to Et2O soln. of F-compd. (-70 °C, 1 h stirring), mixt. was added to pre-cooled (-60 °C) soln. of 2.5 equiv. of B(OMe)3 in Et2O, stirring for 1 h at -60 °C, warming to 20 ° C within 1 h; hydrolysis with 10 % HCl, org. layer was sepd., aq. layer was twice extd. with ether, extracts were combined, dried with MgSO4, evapd. under vac., solid was recrystd. from hot toluene, elem. anal.;
References:
Frohn;Adonin;Bardin;Starichenko [Zeitschrift fur Anorganische und Allgemeine Chemie,2002,vol. 628,# 13,p. 2827 - 2833]