2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE synthesis
- Product Name:2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE
- CAS Number:4424-20-8
- Molecular formula:C10H13N
- Molecular Weight:147.22
130800-04-3
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4424-20-8
133 suppliers
$49.00/100mg
Yield:4424-20-8 100%
Reaction Conditions:
with ammonia at 90; for 3 h;Sealed tube;
Steps:
33 2,3,4,5-tetrahydro-1H-benzo[d]azepine(Compound 33C)
Compound 33B (644 mg, 2 mmol) was added to the sealed tube.Ammonia (5 mL, 17%) was stirred at 90 ° C for 3 hours in a sealed tube.LCMS detected the end of the reaction.The solvent was distilled off under reduced pressure to give Compound 33C(280 mg, 100% yield).
References:
Jiangsu Xiansheng Pharmaceutical Co., Ltd.;Chen Huanming;Liang Bo;Zhao Zhongqiang;Cao Wenjie;Xu Wanmei;Li Qingsong;Wang Jianghuai;Zhang Peng;Jiang Zhaojian;Zhang Guiping;Gao Chunhua;Gong Hongju;Zuo Gaolei CN108250128, 2018, A Location in patent:Paragraph 0606; 0608; 0613; 0614
613-73-0
133 suppliers
$22.80/5g
4424-20-8
133 suppliers
$49.00/100mg
![1,2,4,5-TETRAHYDROBENZO[D]AZEPINE-3-CARBALDEHYDE](/CAS/GIF/215033-43-5.gif)
215033-43-5
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4424-20-8
133 suppliers
$49.00/100mg
7500-53-0
208 suppliers
$27.00/5g
4424-20-8
133 suppliers
$49.00/100mg
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17378-99-3
16 suppliers
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4424-20-8
133 suppliers
$49.00/100mg