2,2'-Bipyridine-4,4'-dicarboxylic acid synthesis
- Product Name:2,2'-Bipyridine-4,4'-dicarboxylic acid
- CAS Number:6813-38-3
- Molecular formula:C12H8N2O4
- Molecular Weight:244.2
6313-54-8
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$8.00/5g
6813-38-3
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$6.00/250mg
Yield:6813-38-3 85%
Reaction Conditions:
with hydrogenchloride;sodium hydroxide;palladium in methanol;water
Steps:
5 Example 5
Example 5 5.00 g of 2-chloroisonicotinic acid and 2.80 g of sodium hydroxide are dissolved in a mixture of 20 ml of water and 16 ml of methanol. Following the addition of 1.02 g of palladium (10% by weight on activated carbon) as catalyst, the mixture is stirred for 6 h at 80-85° C. at 0.1 MPa. The catalyst is then filtered off. Following acidification to pH 1 using hydrochloric acid, the product, 2,2'-bipyridyl-4,4'-dicarboxylic acid, precipitates out as a white solid. This gives 3.3 g (85% yield).
References:
Axiva GmbH US6500956, 2002, B1
1134-35-6
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$5.00/1g
6813-38-3
325 suppliers
$6.00/250mg
1127385-14-1
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6813-38-3
325 suppliers
$6.00/250mg
1134-35-6
298 suppliers
$5.00/1g
6813-38-3
325 suppliers
$6.00/250mg
103946-54-9
90 suppliers
$80.00/50mg
71071-46-0
143 suppliers
$11.00/250mg
6813-38-3
325 suppliers
$6.00/250mg