Carbamic acid, (3-hydroxycyclobutyl)-, 1,1-dimethylethyl ester (9CI) synthesis
- Product Name:Carbamic acid, (3-hydroxycyclobutyl)-, 1,1-dimethylethyl ester (9CI)
- CAS Number:154748-63-7
- Molecular formula:C9H17NO3
- Molecular Weight:187.24
23761-23-1
473 suppliers
$6.00/1g
154748-63-7
105 suppliers
$10.00/250mg
Yield:-
Steps:
Multi-step reaction with 4 steps
1.1: thionyl chloride / dichloromethane / 1.5 h / 0 °C / Reflux
2.1: sodium azide / acetone; water / 1 h / 0 °C
3.1: toluene / 90 °C
3.2: 90 °C
4.1: sodium tetrahydroborate / ethanol / 0.5 h / 0 - 20 °C
References:
AGIOS PHARMACEUTICALS, INC.;LEMIEUX, Rene M.;POPOVICI-MULLER, Janeta;TRAVINS, Jeremy;CAI, Zhenwei;CUI, Dawei;ZHOU, Ding WO2013/107291, 2013, A1
154748-62-6
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154748-63-7
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871014-16-3
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154748-63-7
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130369-04-9
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$49.47/250mgs:
154748-63-7
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389890-43-1
123 suppliers
$60.00/1g
154748-63-7
105 suppliers
$10.00/250mg