(R)-A,A-BIS(3-CHLOROPHENYL)-2-PYRROLIDINEMETHANOL HYDROCHLORIDE synthesis

3synthesis methods

Product Name:(R)-A,A-BIS(3-CHLOROPHENYL)-2-PYRROLIDINEMETHANOL HYDROCHLORIDE
CAS Number:131180-59-1
Molecular formula:C17H17Cl2NO
Molecular Weight:322.23

1-Pyrrolidinecarboxylic acid, 2-[bis(3-chlorophenyl)hydroxymethyl]-, ethyl ester, (2S)-

1370292-86-6
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(R)-A,A-BIS(3-CHLOROPHENYL)-2-PYRROLIDINEMETHANOL HYDROCHLORIDE

131180-59-1
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Yield:131180-59-1 94%

Reaction Conditions:

with methanol;potassium hydroxide for 12 h;Reflux;

References:

Miyakoshi, Hitoshi;Miyahara, Seiji;Yokogawa, Tatsushi;Chong, Khoon Tee;Taguchi, Junko;Endoh, Kanji;Yano, Wakako;Wakasa, Takeshi;Ueno, Hiroyuki;Takao, Yayoi;Nomura, Makoto;Shuto, Satoshi;Nagasawa, Hideko;Fukuoka, Masayoshi [Journal of Medicinal Chemistry,2012,vol. 55,# 7,p. 2960 - 2969] Location in patent:supporting information; experimental part

(7aS)-tetrahydro-1H,3H-Pyrrolo[1,2-c]oxazole-1,3-dione

45736-33-2
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36229-42-2
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$213.00/50ml

131180-59-1
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References

36229-42-2
68 suppliers
$213.00/50ml

131180-59-1
7 suppliers
inquiry

References

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