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ChemicalBook CAS DataBase List 4-amino-N-((4-benzyl-2-morpholinyl)-methyl)-5-chloro-2-ethoxybenzamide
112885-33-3

4-amino-N-((4-benzyl-2-morpholinyl)-methyl)-5-chloro-2-ethoxybenzamide synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 3 h / 80 °C
2: concd. H2SO4 / 1 h / 150 °C
3: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride / CH2Cl2 / 4 h / Ambient temperature

References:

Kato;Morie;Hino;Kon;Naruto;Yoshida;Karasawa;Matsumoto [Journal of Medicinal Chemistry,1990,vol. 33,# 5,p. 1406 - 1413]

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