1-(4-Bromophenylsulfonyl)piperidin-4-one synthesis
- Product Name:1-(4-Bromophenylsulfonyl)piperidin-4-one
- CAS Number:929000-54-4
- Molecular formula:C11H12BrNO3S
- Molecular Weight:318.19
41661-47-6
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$45.00/250mg
98-58-8
256 suppliers
$12.00/5g
929000-54-4
36 suppliers
$54.00/1g
Yield:-
Reaction Conditions:
with pyridine at 20; for 18 h;
Steps:
Compound C0025-1To a solution of piperidin-4-one (1.8 g, 11.74 mmol) in pyridine (30 ml) was added 4-bromobenzene-1-sulfonyl chloride (2 g, 7.83 mmol). The mixture was stirred overnight (about 18 hours) at room temperature. The solvent was removed under reduced pressure. The residue was diluted with CH2Cl2 (100 ml), washed with 3N HCl (100 ml×2), dried over anhydrous Na2SO4 and concentrated to give the title compound as a pale solid (1.3 g, yield: 521, TLC confirmed).
References:
US2010/280057,2010,A1 Location in patent:Page/Page column 34
41979-39-9
116 suppliers
$15.00/10mg
98-58-8
256 suppliers
$12.00/5g
929000-54-4
36 suppliers
$54.00/1g