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ChemicalBook >> CAS DataBase List >> RN486

RN486

RN486 price.
  • $86 - $2500
  • Product name: RN486
  • CAS: 1242156-23-5
  • MF: C35H35FN6O3
  • MW: 606.69
  • EINECS:200-110-4
  • MDL Number:MFCD24682729
  • Synonyms:RN486;6-cyclopropyl-8-fluoro-2-(2-(hydroxyMethyl)-3-(1-Methyl-5-((5-(4-Methylpiperazin-1-yl)pyridin-2-yl)aMiNA)-6-oxo-1,6-dihydropyridin-3-yl)phenyl)isoquiNAlin-1(2H)-one;6-cyclopropyl-8-fluoro-2-(2-(hydroxyMethyl)-3-(1-Methyl-5-(5-(4-Methylpiperazin-1-yl)pyridin-2-ylaMino)-6-oxo-1,6-dihydropyridin-3-yl)phenyl)isoquinolin-1(2H)-one;RN486/RN-486;RN468;6-Cyclopropyl-2-[3-[1,6-dihydro-1-methyl-5-[[5-(4-methyl-1-piperazinyl)-2-pyridinyl]amino]-6-oxo-3-pyridinyl]-2-(hydroxymethyl)phenyl]-8-fluoro-1(2H)-isoquinolinone;RN486 LM-2078;RN486 TFA Salt
24 prices
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Brand
  • AK Scientific
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberY1887
  • Product descriptionRN486
  • Packaging10mg
  • Price$1265
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY1887
  • Product descriptionRN486
  • Packaging25mg
  • Price$2475
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8636
  • Product descriptionRN486
  • Packaging25mg
  • Price$360
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146270
  • Product descriptionRN486 >98%
  • Packaging100mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146270
  • Product descriptionRN486 >98%
  • Packaging250mg
  • Price$2245.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFR65149
  • Product descriptionRN 486
  • Packaging5mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFR65149
  • Product descriptionRN 486
  • Packaging25mg
  • Price$375
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number20536
  • Product descriptionRN-486 ≥98%
  • Packaging1mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20536
  • Product descriptionRN-486 ≥98%
  • Packaging5mg
  • Price$232
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20536
  • Product descriptionRN-486 ≥98%
  • Packaging10mg
  • Price$421
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1814
  • Product descriptionRN486 99.87%
  • Packaging1mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1814
  • Product descriptionRN486 99.87%
  • Packaging5mg
  • Price$156
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1814
  • Product descriptionRN486 99.87%
  • Packaging10mg
  • Price$216
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1814
  • Product descriptionRN486 99.87%
  • Packaging25mg
  • Price$432
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1814
  • Product descriptionRN486 99.87%
  • Packaging50mg
  • Price$660
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004125
  • Product descriptionRN486 98+%
  • Packaging5mg
  • Price$112
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y1887 RN486 10mg $1265 2021-12-16 Buy
AK Scientific Y1887 RN486 25mg $2475 2021-12-16 Buy
ApexBio Technology A8636 RN486 25mg $360 2021-12-16 Buy
Biorbyt Ltd orb146270 RN486 >98% 100mg $1208.7 2021-12-16 Buy
Biorbyt Ltd orb146270 RN486 >98% 250mg $2245.7 2021-12-16 Buy
Biosynth Carbosynth FR65149 RN 486 5mg $125 2021-12-16 Buy
Biosynth Carbosynth FR65149 RN 486 25mg $375 2021-12-16 Buy
Cayman Chemical 20536 RN-486 ≥98% 1mg $86 2024-03-01 Buy
Cayman Chemical 20536 RN-486 ≥98% 5mg $232 2024-03-01 Buy
Cayman Chemical 20536 RN-486 ≥98% 10mg $421 2024-03-01 Buy
ChemScene CS-1814 RN486 99.87% 1mg $96 2021-12-16 Buy
ChemScene CS-1814 RN486 99.87% 5mg $156 2021-12-16 Buy
ChemScene CS-1814 RN486 99.87% 10mg $216 2021-12-16 Buy
ChemScene CS-1814 RN486 99.87% 25mg $432 2021-12-16 Buy
ChemScene CS-1814 RN486 99.87% 50mg $660 2021-12-16 Buy
Crysdot CD31004125 RN486 98+% 5mg $112 2021-12-16 Buy

Properties

Boiling point :868.6±65.0 °C(Predicted)
Density :1.378±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥30.35 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
form :solid
pka :13.95±0.10(Predicted)
color :Off-white to light yellow
CAS DataBase Reference :1242156-23-5

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

RN 486 is a Bruton’s tyrosine kinase (Btk) inhibitor, blocking receptor cross-linking-induced degranulation in mast cells. May be used in the prevention of arthritis and other autoimmune diseases.

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