PHA-848125
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- $62 - $4173.5
- Product name: PHA-848125
- CAS: 802539-81-7
- MF: C25H32N8O
- MW: 460.57
- EINECS:-0
- MDL Number:MFCD17169990
- Synonyms:PHA-848125;4,5-Dihydro-N,1,4,4-tetramethyl-8-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide;Milciclib;PHA-848125 (Milciclib);Milciclib (PHA-848125);N,1,4,4-tetramethyl-8-(4-(4-methylpiperazin-1-yl)phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide;4,5-Dihydro-N,1,4,4-tetramethyl-8-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide PHA 848125;4,5-Dihydro-N,1,4,4-tetramethyl-8-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-1H-pyrazolo[4,3-h]
27 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 1mg
- 2.5mg
- 5MG
- 10mg
- 50mg
- 100mg
- 250mg
- 1000mg
- 1g
- 10mM(in 1mL DMSO)
- 5g
- ManufacturerAK Scientific
- Product numberY0330
- Product descriptionPHA-848125
- Packaging10mg
- Price$430
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0330
- Product descriptionPHA-848125
- Packaging1mg
- Price$166
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002463
- Product descriptionPHA-848125 95.00%
- Packaging5MG
- Price$459.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8501
- Product descriptionPHA-848125
- Packaging5mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8501
- Product descriptionPHA-848125
- Packaging10mM(in 1mL DMSO)
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8501
- Product descriptionPHA-848125
- Packaging10mg
- Price$260
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181086
- Product descriptionPHA-848125(Milciclib) >98%
- Packaging100mg
- Price$1283.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181086
- Product descriptionPHA-848125(Milciclib) >98%
- Packaging250mg
- Price$2097.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181086
- Product descriptionPHA-848125(Milciclib) >98%
- Packaging1000mg
- Price$4173.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21474
- Product descriptionPHA-848125 ≥98%
- Packaging1mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21474
- Product descriptionPHA-848125 ≥98%
- Packaging5mg
- Price$135
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21474
- Product descriptionPHA-848125
- Packaging10mg
- Price$239
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0579
- Product descriptionMilciclib 99.92%
- Packaging5mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0579
- Product descriptionMilciclib 99.92%
- Packaging10mg
- Price$396
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0579
- Product descriptionMilciclib 99.92%
- Packaging50mg
- Price$1030
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0579
- Product descriptionMilciclib 99.92%
- Packaging100mg
- Price$1980
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | Y0330 | PHA-848125 | 10mg | $430 | 2021-12-16 | Buy |
| AK Scientific | Y0330 | PHA-848125 | 1mg | $166 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002463 | PHA-848125 95.00% | 5MG | $459.8 | 2021-12-16 | Buy |
| ApexBio Technology | A8501 | PHA-848125 | 5mg | $190 | 2021-12-16 | Buy |
| ApexBio Technology | A8501 | PHA-848125 | 10mM(in 1mL DMSO) | $220 | 2021-12-16 | Buy |
| ApexBio Technology | A8501 | PHA-848125 | 10mg | $260 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181086 | PHA-848125(Milciclib) >98% | 100mg | $1283.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181086 | PHA-848125(Milciclib) >98% | 250mg | $2097.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181086 | PHA-848125(Milciclib) >98% | 1000mg | $4173.5 | 2021-12-16 | Buy |
| Cayman Chemical | 21474 | PHA-848125 ≥98% | 1mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 21474 | PHA-848125 ≥98% | 5mg | $135 | 2024-03-01 | Buy |
| Cayman Chemical | 21474 | PHA-848125 | 10mg | $239 | 2024-03-01 | Buy |
| ChemScene | CS-0579 | Milciclib 99.92% | 5mg | $240 | 2021-12-16 | Buy |
| ChemScene | CS-0579 | Milciclib 99.92% | 10mg | $396 | 2021-12-16 | Buy |
| ChemScene | CS-0579 | Milciclib 99.92% | 50mg | $1030 | 2021-12-16 | Buy |
| ChemScene | CS-0579 | Milciclib 99.92% | 100mg | $1980 | 2021-12-16 | Buy |
Properties
Melting point :190 °C
Density :1.33
storage temp. :Store at -20°C
solubility :≥23.05 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :14.44±0.40(Predicted)
color :Light yellow to yellow
Density :1.33
storage temp. :Store at -20°C
solubility :≥23.05 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :14.44±0.40(Predicted)
color :Light yellow to yellow
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
PHA-848125 is an ATP-competitive inhibitor of cyclin-dependent kinases (Cdks) that potently inhibits Cdk2/cyclin A (IC50 = 45 nM). It is at least 3-fold less potent at Cdks 1, 3, 4, 5, and 7. PHA-848125 is orally available and displays efficacy in suppressing the growth of cancer cells or tumor xenografts in animals.Related product price
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