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ChemicalBook >> CAS DataBase List >> IC 261

IC 261

IC 261 price.
  • $15 - $1450
  • Product name: IC 261
  • CAS: 186611-52-9
  • MF: C18H17NO4
  • MW: 311.335
  • EINECS:
  • MDL Number:MFCD00118156
  • Synonyms:SU5607, 1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one;1,3-Dihydro-3-[(2,4,6-triMethoxyphenyl)Methylene]-2H-indol-2-one, SU5607;SU-5607 IC 261;(E)-3-(2,4,6-trimethoxybenzylidene)indolin-2-one;IC261, >98%;IC-261(SU-5607);IC261 - CAS 186611-52-9 - Calbiochem;IC261;SU5607;IC 261;SU 5607
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  • ManufacturerAmbeed
  • Product numberA267194
  • Product descriptionIC 261 98+%
  • Packaging1mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA267194
  • Product descriptionIC 261 98+%
  • Packaging5mg
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA267194
  • Product descriptionIC 261 98+%
  • Packaging10mg
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA267194
  • Product descriptionIC 261 98+%
  • Packaging25mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA267194
  • Product descriptionIC 261 98+%
  • Packaging50mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA267194
  • Product descriptionIC 261 98+%
  • Packaging100mg
  • Price$86
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA267194
  • Product descriptionIC 261 98+%
  • Packaging250mg
  • Price$129
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA267194
  • Product descriptionIC 261 98+%
  • Packaging1g
  • Price$328
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6108
  • Product descriptionIC 261
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6108
  • Product descriptionIC 261
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6108
  • Product descriptionIC 261
  • Packaging50mg
  • Price$680
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS033319
  • Product descriptionIC 261 ≥98%
  • Packaging1mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS033319
  • Product descriptionIC 261 ≥98%
  • Packaging5mg
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS033319
  • Product descriptionIC 261 ≥98%
  • Packaging10mg
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS033319
  • Product descriptionIC 261 ≥98%
  • Packaging25mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS033319
  • Product descriptionIC 261 ≥98%
  • Packaging50mg
  • Price$45
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A267194 IC 261 98+% 1mg $15 2021-12-16 Buy
Ambeed A267194 IC 261 98+% 5mg $20 2021-12-16 Buy
Ambeed A267194 IC 261 98+% 10mg $27 2021-12-16 Buy
Ambeed A267194 IC 261 98+% 25mg $35 2021-12-16 Buy
Ambeed A267194 IC 261 98+% 50mg $45 2021-12-16 Buy
Ambeed A267194 IC 261 98+% 100mg $86 2021-12-16 Buy
Ambeed A267194 IC 261 98+% 250mg $129 2021-12-16 Buy
Ambeed A267194 IC 261 98+% 1g $328 2021-12-16 Buy
ApexBio Technology B6108 IC 261 5mg $90 2021-12-16 Buy
ApexBio Technology B6108 IC 261 10mg $160 2021-12-16 Buy
ApexBio Technology B6108 IC 261 50mg $680 2021-12-16 Buy
Arctom AS033319 IC 261 ≥98% 1mg $15 2021-12-16 Buy
Arctom AS033319 IC 261 ≥98% 5mg $20 2021-12-16 Buy
Arctom AS033319 IC 261 ≥98% 10mg $27 2021-12-16 Buy
Arctom AS033319 IC 261 ≥98% 25mg $35 2021-12-16 Buy
Arctom AS033319 IC 261 ≥98% 50mg $45 2021-12-16 Buy

Properties

Melting point :214 °C
storage temp. :protect from light
solubility :DMSO: 18 mg/mL soluble
form :solid
color :yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

IC261 is a reversible, ATP-competitive inhibitor of casein kinase 1 (CK1) that inhibits CK1δ and CK1? (IC50 = ~1 μM for both), as well as CK1α (IC50 = 16 μM). It is at least 100-fold less effective against PKA, p34cdc2, and p55fyn. IC 261, at 1 μM, inhibits cytokinesis in primary mouse embryo fibroblasts. IC261 is used to elucidate the role of CK1 in cells and in whole organisms.

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