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ChemicalBook >> CAS DataBase List >> E 7010

E 7010

E 7010 price.
  • $38 - $2245.7
  • Product name: E 7010
  • CAS: 141430-65-1
  • MF: C18H17N3O4S
  • MW: 371.41
  • EINECS:256-495-9
  • MDL Number:MFCD00910291
  • Synonyms:E 7010;N-[2-(4-HYDROXYANILINO)PYRIDIN-3-YL]-4-METHOXYBENZENE-1-SULFONAMIDE;N-[2-[(4-Hydroxyphenyl)amino]-3-pyridyl]-4-methoxybenzenesulfonamide;BenzenesulfonaMide, N-[2-[(4-hydroxyphenyl)aMino]-3-pyridinyl]-4-Methoxy-;ABT-751 (E7010);N-(2-(4-hydroxyphenylamino)pyridin-3-yl)-4-methoxybenzenesulfonamide;ABT-751 (E;E7010(ABT-751)
36 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TCI Chemical
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1000mg
  • 10mM(in 1mL DMSO)
  • 1g
  • ManufacturerAK Scientific
  • Product numberX7522
  • Product descriptionN-(2-(4-hydroxyphenylamino)pyridin-3-yl)-4-methoxybenzenesulfonamide
  • Packaging1g
  • Price$1149
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA110139
  • Product descriptionABT-751 98+%
  • Packaging5mg
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA110139
  • Product descriptionABT-751 98+%
  • Packaging10mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA110139
  • Product descriptionABT-751 98+%
  • Packaging25mg
  • Price$94
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA110139
  • Product descriptionABT-751 98+%
  • Packaging50mg
  • Price$122
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA110139
  • Product descriptionABT-751 98+%
  • Packaging100mg
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA110139
  • Product descriptionABT-751 98+%
  • Packaging250mg
  • Price$325
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA110139
  • Product descriptionABT-751 98+%
  • Packaging1g
  • Price$816
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005108
  • Product descriptionABT-751 95.00%
  • Packaging10MG
  • Price$253.05
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1493
  • Product descriptionABT-751(E7010)
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1493
  • Product descriptionABT-751(E7010)
  • Packaging10mM(in 1mL DMSO)
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1493
  • Product descriptionABT-751(E7010)
  • Packaging50mg
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1493
  • Product descriptionABT-751(E7010)
  • Packaging100mg
  • Price$470
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS028237
  • Product descriptionABT-751 ≥98%
  • Packaging5mg
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS028237
  • Product descriptionABT-751 ≥98%
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS028237
  • Product descriptionABT-751 ≥98%
  • Packaging25mg
  • Price$93
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X7522 N-(2-(4-hydroxyphenylamino)pyridin-3-yl)-4-methoxybenzenesulfonamide 1g $1149 2021-12-16 Buy
Ambeed A110139 ABT-751 98+% 5mg $38 2021-12-16 Buy
Ambeed A110139 ABT-751 98+% 10mg $66 2021-12-16 Buy
Ambeed A110139 ABT-751 98+% 25mg $94 2021-12-16 Buy
Ambeed A110139 ABT-751 98+% 50mg $122 2021-12-16 Buy
Ambeed A110139 ABT-751 98+% 100mg $226 2021-12-16 Buy
Ambeed A110139 ABT-751 98+% 250mg $325 2021-12-16 Buy
Ambeed A110139 ABT-751 98+% 1g $816 2021-12-16 Buy
American Custom Chemicals Corporation API0005108 ABT-751 95.00% 10MG $253.05 2021-12-16 Buy
ApexBio Technology A1493 ABT-751(E7010) 10mg $85 2021-12-16 Buy
ApexBio Technology A1493 ABT-751(E7010) 10mM(in 1mL DMSO) $110 2021-12-16 Buy
ApexBio Technology A1493 ABT-751(E7010) 50mg $330 2021-12-16 Buy
ApexBio Technology A1493 ABT-751(E7010) 100mg $470 2021-12-16 Buy
Arctom AS028237 ABT-751 ≥98% 5mg $38 2021-12-16 Buy
Arctom AS028237 ABT-751 ≥98% 10mg $65 2021-12-16 Buy
Arctom AS028237 ABT-751 ≥98% 25mg $93 2021-12-16 Buy

Properties

Melting point :162 °C(dec.)
Boiling point :551.0±60.0 °C(Predicted)
Density :1.427
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :insoluble in H2O; ≥18.55 mg/mL in DMSO; ≥25.53 mg/mL in EtOH with ultrasonic
form :powder to crystal
pka :7.86±0.40(Predicted)
color :White to Yellow to Orange

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P281 Use personal protective equipment as required.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P314 Get medical advice/attention if you feel unwell.
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

ABT-751 is a tubulin polymerization inhibitor that binds to the colchicine binding site on β-tubulin (Ki = 3.3 μM). It inhibits tubulin polymerization in a concentration-dependent manner and inhibits growth of 26 human tumor cell lines (IC50s = 0.06-0.08 μg/ml). ABT-751 (100 mg/kg, p.o.) induces tumor regression in NB-1382 neuroblastoma, IRS56 rhabdomyosarcoma, and KT-6 Wilms mouse xenograft models. It also induces tumor endothelial cell retraction and reduces tumor perfusion, but not muscle perfusion, in a 9L rat glioma subcutaneous tumor model.

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