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ChemicalBook >> CAS DataBase List >> Cyclosporin H

Cyclosporin H

Cyclosporin H price.
  • $56 - $1880
  • Product name: Cyclosporin H
  • CAS: 83602-39-5
  • MF: C62H111N11O12
  • MW: 1202.61
  • EINECS:
  • MDL Number:MFCD04039488
  • Synonyms:CYCLOSPORIN H;Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-D-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl];5-(N-Methyl-D-valine)cyclosporin A;Cyclo[L-alanyl-D-alanyl-N-Methyl-L- leucyl-N-Methyl-L-leucyl-N-Methyl-D-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-diMethyl-L-2-aMinooctanoyl-L-2-aMinobutanoyl-N-Methylglycyl-N-Methyl-L-leucyl-L-valyl-N-Methyl-L-leucyl];Sandoz 37-839;Cyclosporin H, >=95%;Cyclosporine IMpurity-H;5-(N-Methyl-D-valine)cyclosporine A
33 prices
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Brand
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 2mg
  • 2.5mg
  • 1mg
  • 5
  • 5mg
  • 10mg
  • 25mg
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  • 0.05g
  • 100mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0447-M005
  • Product descriptionCyclosporin H ≥97%(HPLC)
  • Packaging5mg
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1251
  • Product descriptionCyclosporin H 98%
  • Packaging0.05g
  • Price$760
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV1784
  • Product descriptionCyclosporin H
  • Packaging25mg
  • Price$383
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA219301
  • Product description(3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone 99%
  • Packaging1mg
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA219301
  • Product description(3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone 99%
  • Packaging5mg
  • Price$126
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA219301
  • Product description(3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone 99%
  • Packaging10mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA219301
  • Product description(3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone 99%
  • Packaging25mg
  • Price$311
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA219301
  • Product description(3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone 99%
  • Packaging50mg
  • Price$463
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA219301
  • Product description(3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone 99%
  • Packaging100mg
  • Price$687
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5921
  • Product descriptionCyclosporin H
  • Packaging1mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSY068851
  • Product descriptionCyclosporinH,95%,fromMicromonospora ≥97%
  • Packaging10mg
  • Price$220.91
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1971
  • Product descriptionCyclosporin H
  • Packaging2.5mg
  • Price$89
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1971
  • Product descriptionCyclosporin H
  • Packaging10mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1971
  • Product descriptionCyclosporin H
  • Packaging25mg
  • Price$389
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1971
  • Product descriptionCyclosporin H
  • Packaging100mg
  • Price$1090
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180887
  • Product descriptionCyclosporin H >98%
  • Packaging100mg
  • Price$1283.5
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0447-M005 Cyclosporin H ≥97%(HPLC) 5mg $320 2021-12-16 Buy
AHH API-1251 Cyclosporin H 98% 0.05g $760 2021-12-16 Buy
AK Scientific V1784 Cyclosporin H 25mg $383 2021-12-16 Buy
Ambeed A219301 (3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone 99% 1mg $56 2021-12-16 Buy
Ambeed A219301 (3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone 99% 5mg $126 2021-12-16 Buy
Ambeed A219301 (3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone 99% 10mg $189 2021-12-16 Buy
Ambeed A219301 (3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone 99% 25mg $311 2021-12-16 Buy
Ambeed A219301 (3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone 99% 50mg $463 2021-12-16 Buy
Ambeed A219301 (3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone 99% 100mg $687 2021-12-16 Buy
ApexBio Technology B5921 Cyclosporin H 1mg $110 2021-12-16 Buy
Arctom SY068851 CyclosporinH,95%,fromMicromonospora ≥97% 10mg $220.91 2021-12-16 Buy
AvaChem 1971 Cyclosporin H 2.5mg $89 2021-12-16 Buy
AvaChem 1971 Cyclosporin H 10mg $189 2021-12-16 Buy
AvaChem 1971 Cyclosporin H 25mg $389 2021-12-16 Buy
AvaChem 1971 Cyclosporin H 100mg $1090 2021-12-16 Buy
Biorbyt Ltd orb180887 Cyclosporin H >98% 100mg $1283.5 2021-12-16 Buy

Properties

Melting point :148-151°C
Boiling point :1293.8±65.0 °C(Predicted)
Density :1.016±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly, Heated, Sonicated)
pka :13.32±0.70(Predicted)
form :powder
color :white to beige
optical activity :[α]/D -100 to -115°, c = 0.5 in methanol
biological source :Tolypocladium inflatum

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Cyclosporin H is a natural cyclic undecapeptide that selectively antagonizes the formyl peptide receptor at concentrations ranging from 0.1 to 10 μM. Unlike cyclosporin A , cyclosporin H does not bind cyclophilin to evoke an immunosuppressant response. Cyclosporin H has been reported to inhibit phorbol ester-mediated effects in mouse skin and block calcium/calmodulin-dependent EF-2 phosphorylation in vitro.

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