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ChemicalBook >> CAS DataBase List >> Amphotericin B

Amphotericin B

Amphotericin B price.
  • $7 - $27250
  • Product name: Amphotericin B
  • CAS: 1397-89-3
  • MF: C47H73NO17
  • MW: 924.08
  • EINECS:215-742-2
  • MDL Number:MFCD00877763
  • Synonyms:FUNGIZONE(R);AMPHOTERCIN B;AMPHOTERICIN B;AMPHOTERICIN B SOLUBILIZED;AMPHOTERICIN B, SOLUBLE;AMPHOTERICIN B, STREPTOMYCES NODOSUS;AMPHOTERICIN B, STREPTOMYCES SPECIES;AMPHOZONE
65 prices
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Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • AvaChem
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • Frontier Specialty Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • y0000005
  • 20mg
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  • y0001361
  • 500mg
  • y0001014
  • 100mg
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  • 1g
  • 50mg
  • 5g
  • 100
  • 25g
  • 50ml
  • 100g
  • 10mM(in 1mL DMSO)
  • 10g
  • 20ml
  • 100ml
  • ManufacturerAHH
  • Product numberAPI-1204
  • Product descriptionAmphotericin B 98%
  • Packaging10g
  • Price$710
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10140
  • Product descriptionAmphotericin B
  • Packaging1g
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61491
  • Product descriptionAmphotericin B, Streptomyces nodosus
  • Packaging100mg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67049
  • Product descriptionAmphotericin B, 250 μg/ml in distilled water, sterile-filtered
  • Packaging50ml
  • Price$127.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61491
  • Product descriptionAmphotericin B, Streptomyces nodosus
  • Packaging1g
  • Price$197
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61491
  • Product descriptionAmphotericin B, Streptomyces nodosus
  • Packaging5g
  • Price$829
  • Updated2024-03-01
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  • ManufacturerAmbeed
  • Product numberA119196
  • Product description(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylicacid ≥750ug/mg
  • Packaging250mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA119196
  • Product description(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylicacid ≥750ug/mg
  • Packaging1g
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA119196
  • Product description(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylicacid ≥750ug/mg
  • Packaging5g
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA119196
  • Product description(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylicacid ≥750ug/mg
  • Packaging25g
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA119196
  • Product description(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylicacid ≥750ug/mg
  • Packaging100g
  • Price$624
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001473
  • Product descriptionAMPHOTERICIN B 95.00%
  • Packaging250MG
  • Price$202.65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001473
  • Product descriptionAMPHOTERICIN B 95.00%
  • Packaging1G
  • Price$635.71
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001473
  • Product descriptionAMPHOTERICIN B 95.00%
  • Packaging5G
  • Price$918.11
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1885
  • Product descriptionAmphotericin B
  • Packaging100mg
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1885
  • Product descriptionAmphotericin B
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1204 Amphotericin B 98% 10g $710 2021-12-16 Buy
AK Scientific J10140 Amphotericin B 1g $100 2021-12-16 Buy
Alfa Aesar J61491 Amphotericin B, Streptomyces nodosus 100mg $68 2024-03-01 Buy
Alfa Aesar J67049 Amphotericin B, 250 μg/ml in distilled water, sterile-filtered 50ml $127.65 2024-03-01 Buy
Alfa Aesar J61491 Amphotericin B, Streptomyces nodosus 1g $197 2024-03-01 Buy
Alfa Aesar J61491 Amphotericin B, Streptomyces nodosus 5g $829 2024-03-01 Buy
Ambeed A119196 (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylicacid ≥750ug/mg 250mg $7 2021-12-16 Buy
Ambeed A119196 (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylicacid ≥750ug/mg 1g $16 2021-12-16 Buy
Ambeed A119196 (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylicacid ≥750ug/mg 5g $65 2021-12-16 Buy
Ambeed A119196 (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylicacid ≥750ug/mg 25g $189 2021-12-16 Buy
Ambeed A119196 (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylicacid ≥750ug/mg 100g $624 2021-12-16 Buy
American Custom Chemicals Corporation API0001473 AMPHOTERICIN B 95.00% 250MG $202.65 2021-12-16 Buy
American Custom Chemicals Corporation API0001473 AMPHOTERICIN B 95.00% 1G $635.71 2021-12-16 Buy
American Custom Chemicals Corporation API0001473 AMPHOTERICIN B 95.00% 5G $918.11 2021-12-16 Buy
ApexBio Technology B1885 Amphotericin B 100mg $53 2021-12-16 Buy
ApexBio Technology B1885 Amphotericin B 10mM(in 1mL DMSO) $55 2021-12-16 Buy

Properties

Melting point :>170°C
alpha :D24 +333° (acidic DMF); -33.6° (0.1N methanolic HCl)
Boiling point :804.34°C (rough estimate)
Density :1.34
refractive index :1.5280 (estimate)
storage temp. :2-8°C
solubility :sterile water: 20 mg/mL as a stock solution. Stock solutions should be stored at −20°C. Stable at 37°C for 3 days.
form :powder
pka :pKa ～5.7(DMF/H2O) (Uncertain)
color :yellow
Water Solubility :<0.1 g/100 mL at 21 ºC
Sensitive :Moisture & Light Sensitive
Merck :13,590
BRN :78342
Stability :Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
InChIKey :APKFDSVGJQXUKY-INPOYWNPSA-N
CAS DataBase Reference :1397-89-3(CAS DataBase Reference)
EPA Substance Registry System :Amphotericin B (1397-89-3)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P314 Get medical advice/attention if you feel unwell.
P501 Dispose of contents/container to..…

Description

Amphotericin B is a classic antifungal polyene macrolide that has been used in the treatment of systemic fungal infections, primarily caused by C. albicans, A. fumigatus, and parasitic L. protozoans, as well as in tissue culture to prevent fungi from contaminating cell cultures. Amphotericin B binds with ergosterol, the main component of fungal cell membranes, forming a transmembrane channel that results in altered plasma membrane permeability and leakage of vital cytoplasmic components, such as K+, ultimately inducing cell death. Because prolonged use of amphotericin B is associated with infusion-related events and nephrotoxicity, lipid-based formulations have been devised for more favorable clinical relevance.