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ChemicalBook >> CAS DataBase List >> (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

$48 - $21666
Product name: (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride
CAS: 149690-12-0
MF: C20H26ClNO2
MW: 347.88
EINECS:695-675-7
MDL Number:MFCD27955983
Synonyms:(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate HCl;LCZ696 Intermediate2;LCZ698;[1,1'-Biphenyl]-4-pentanoic acid, γ-amino-α-methyl-, ethyl ester, hydrochloride (1:1), (αR,γS)-;(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate;(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride;(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride (1:1);(2R, 4S) - ethyl 5- ([1,1'- biphenyl]-4- group) -4- amino -2- methyl valerate hydrochloride

Price19 Properties Safety Information Description

19 prices

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Brand

AccelPharmtech
AK Scientific
Alichem
Ambeed
Chemenu
Crysdot
Labseeker
TRC

Package

50mg
1G
5G
10g
25G
100g
1000g
1kg

ManufacturerAccelPharmtech
Product numberXP1500
Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%
Packaging1G
Price$230
Updated2021-12-16
Buy

ManufacturerAccelPharmtech
Product numberXP1500
Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%
Packaging5G
Price$280
Updated2021-12-16
Buy

ManufacturerAccelPharmtech
Product numberXP1500
Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%
Packaging25G
Price$710
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2498DC
Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride
Packaging25g
Price$870
Updated2021-12-16
Buy

ManufacturerAlichem
Product number149690120
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride
Packaging5g
Price$157.5
Updated2021-12-16
Buy

ManufacturerAlichem
Product number149690120
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride
Packaging10g
Price$250
Updated2021-12-16
Buy

ManufacturerAlichem
Product number149690120
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride
Packaging25g
Price$490
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA249066
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
Packaging1g
Price$48
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA249066
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
Packaging5g
Price$135
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA249066
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
Packaging10g
Price$241
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA249066
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
Packaging25g
Price$404
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA249066
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
Packaging100g
Price$1192
Updated2021-12-16
Buy

ManufacturerChemenu
Product numberCM244548
Product description(2R,4S)-Ethyl5-([1,1''-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
Packaging1000g
Price$1748
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD12139848
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
Packaging1g
Price$50
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD12139848
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
Packaging5g
Price$150
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD12139848
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
Packaging10g
Price$250
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AccelPharmtech	XP1500	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%	1G	$230	2021-12-16	Buy
AccelPharmtech	XP1500	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%	5G	$280	2021-12-16	Buy
AccelPharmtech	XP1500	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%	25G	$710	2021-12-16	Buy
AK Scientific	2498DC	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride	25g	$870	2021-12-16	Buy
Alichem	149690120	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride	5g	$157.5	2021-12-16	Buy
Alichem	149690120	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride	10g	$250	2021-12-16	Buy
Alichem	149690120	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride	25g	$490	2021-12-16	Buy
Ambeed	A249066	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%	1g	$48	2021-12-16	Buy
Ambeed	A249066	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%	5g	$135	2021-12-16	Buy
Ambeed	A249066	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%	10g	$241	2021-12-16	Buy
Ambeed	A249066	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%	25g	$404	2021-12-16	Buy
Ambeed	A249066	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%	100g	$1192	2021-12-16	Buy
Chemenu	CM244548	(2R,4S)-Ethyl5-([1,1''-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%	1000g	$1748	2021-12-16	Buy
Crysdot	CD12139848	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%	1g	$50	2021-12-16	Buy
Crysdot	CD12139848	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%	5g	$150	2021-12-16	Buy
Crysdot	CD12139848	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%	10g	$250	2021-12-16	Buy

Next Last

Properties

Melting point :155 - 162°C
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
Stability :Hygroscopic
InChI :InChI=1/C20H25NO2.ClH/c1-3-23-20(22)15(2)13-19(21)14-16-9-11-18(12-10-16)17-7-5-4-6-8-17;/h4-12,15,19H,3,13-14,21H2,1-2H3;1H/t15-,19+;/s3
InChIKey :MYJTZLYRAWUSLB-MTPCZXHRNA-N
SMILES :C(C1C=CC(C2C=CC=CC=2)=CC=1)[C@@H](N)C[C@@H](C)C(=O)OCC.Cl |&1:13,16,r|

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is used as a reagent in the synthesis of LCZ696, an angiotensin II receptor and neprilysin receptor dual inhibitor. (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is also used as a reagent in the preparation of novel NEP inhibitor prodrugs for the treatment of hypertension and cardiovascular diseases.

More related product prices

Sacubitril Impurity 7 AHU-377 (heMicalciuM salt) Valsartan (R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- N-[2’-(1H-tetrazol-5-yl)biphenyl-4-yl methyl]-N-Valeryl-(L)-Valine benzyl ester sacubitril (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoic acid 1426129-50-1 enantioMer BOC-D-4,4'-BIPHENYLALANINE Valsartan n-Propyl 5717-37-3 L-Valine, N-(1-oxopentyl-d9)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]- 4'-Methyl-2-cyanobiphenyl LCZ696 InteMediate 5-[2-(4'-METHYLBIPHENYL)]TETRAZOLE valsartan S)-2-(((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)aMino)-3- Methylbutanoic acid N-[2’-(1H-tetrazol-5-yl)biphenyl-4-yl methyl]-N-Valeryl-(L)-Valine methyl ester

Suppliers and manufacturers

Hebei Junhua Import and Export Co., LTD

$0.00 /1kg
(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride CAS:149690-12-0

career henan chemical co

$100.00 /1KG
(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate CAS:149690-12-0

ChemExpress

Capot Chemical Co.,Ltd.

Shanghai Daken Advanced Materials Co.,Ltd

Beijing Cooperate Pharmaceutical Co.,Ltd

Henan Tianfu Chemical Co.,Ltd.

ATK CHEMICAL COMPANY LIMITED

Jinan Finer Chemical Co., Ltd

HubeiwidelychemicaltechnologyCo.,Ltd

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(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

Properties

Safety Information

Description

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