1-Dodecanol
Product identifier
- Product name: 1-Dodecanol
- CBnumber: CB1334632
- CAS: 112-53-8
- EINECS Number: 203-982-0
- Synonyms: 1-Dodecanol,Lauryl Alcohol
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Eye irritation, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
Label elements
Pictogram(s)
- Signal wordWarning
H315 Causes skin irritation
H319 Causes serious eye irritation
H320 Causes eye irritation
H371 May cause damage to organs
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P321 Specific treatment (see … on this label).
P391 Collect spillage. Hazardous to the aquatic environment
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…
P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: 1-Dodecanol
- Synonyms: 1-Dodecanol,Lauryl Alcohol
- CAS: 112-53-8
- EC number: 203-982-0
- MF: C12H26O
- MW: 186.33
Description of first aid measures
If inhaledFresh air, rest. Seek medical attention if you feel unwell.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
Rinse with plenty of water for several minutes (remove contact lenses if easily possible).
Rinse mouth. Rest. Do NOT induce vomiting. Seek medical attention if you feel unwell.
Most important symptoms and effects, both acute and delayed
Liquid will cause burning of the eyes and may irritate skin. (USCG, 1999)
Indication of any immediate medical attention and special treatment needed
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Higher alcohols (>3 carbons) and related compounds
Extinguishing media
Wear self contained breathing apparatus for fire fighting if necessary.
Specific Hazards Arising from the Chemical
Combustible.
Advice for firefighters
Use water, dry powder, carbon dioxide, alcohol-resistant foam.
NFPA 704
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Ventilation. Sweep spilled substance into sealable containers. If liquid: collect leaking liquid in containers. Absorb remaining liquid in inert absorbent. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Ventilation. Sweep spilled substance into sealable containers. If liquid: collect leaking liquid in containers. Absorb remaining liquid in inert absorbent. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Accidental Release Measures: ... Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
Precautions for safe handling
NO contact with hot surfaces. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Cool. Well closed. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.Keep tightly closed. Store in a cool dry place.
Control parameters
Occupational Exposure limit values| Component | Dodecan-1-ol | |||
|---|---|---|---|---|
| CAS No. | 112-53-8 | |||
| Limit value - Eight hours | Limit value - Short term | |||
| ppm | mg/m3 | ppm | mg/m3 | |
| Germany (AGS) | 20 (1) | 155 (1) | 20 (1)(2) | 155 (1)(2) |
| Latvia | ? | 10 | ? | ? |
| Remarks | ||||
| Germany (AGS) | (1) Inhalable aerosol and vapour (2) 15 minutes reference period | |||
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear safety spectacles.
Protective gloves.
Use ventilation.
no data available
Information on basic physicochemical properties
- Physical stateLiquid
- ColourAPHA: ≤10
- Odour
CHARACTERISTIC FATTY ODOR; UNPLEASANT AT HIGH CONCN BUT DELICATE & FLORAL ON DILUTION
- Melting point/freezing point
24 °C. Atm. press.:Ca. 101.3 kPa. Remarks:Pour point.
- Boiling point or initial boiling point and boiling range
229 °C. Atm. press.:101.3 hPa. Remarks:Equilibrium boiling point (corrected).
- Flammability
Combustible.
- Lower and upper explosion limit/flammability limit4%
- Flash point
Ca. 134.8 °C. Atm. press.:101.3 kPa.
- Auto-ignition temperature
Ca. 275 °C. Atm. press.:Ca. 1 atm.
- Decomposition temperature
no data available
- pH
no data available
- Kinematic viscosity
kinematic viscosity (in mm2/s) = 11.251. Temperature:40°C.
- Solubilitywater: slightly soluble1g/L at 23°C
- Partition coefficient n-octanol/water
log Pow = 5.4. Temperature:23 °C.
- Vapour pressure0.1 mm Hg ( 20 °C)
- Density and/or relative density
0.9 g/cm3. Temperature:16 °C.
- Relative vapour density
7.4 (vs air)
- Particle characteristics
no data available
Reactivity
Reacts violently with oxidizing materials and acids.
Chemical stability
no data available
Possibility of hazardous reactions
Combustible when it is exposed to heat or flame.DODECANOL is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.
Conditions to avoid
no data available
Incompatible materials
Incompatible materials: Strong oxidizing agents.
Hazardous decomposition products
When heated to decomposition it emits acrid smoke and fumes.
Acute toxicity
- Oral: LD50 Rat oral 12,800 mg/kg
- Inhalation: LC50 Rat inhalation >1050 mg/cu m (138 ppm)
- Dermal: LD50 - rabbit (male/female) - 8 000 - 12 000 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the skin, eyes and possibly the respiratory tract. If swallowed the substance may cause vomiting and could result in aspiration pneumonitis.
STOT-repeated exposure
See Notes.
Aspiration hazard
No indication can be given whether a harmful concentration in the air will be reached.
Toxicity
- Toxicity to fish: LC50 - Pimephales promelas - 1.01 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 0.765 mg/L - 48 h.
- Toxicity to algae: EC50 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - 0.33 mg/L - 72 h.
- Toxicity to microorganisms: EC0 - Pseudomonas putida - > 10 000 mg/L - 30 min.
Persistence and degradability
AEROBIC: A 5-day theoretical BOD of 20% was observed for 1-dodecanol in an aerobic screening test using a sewage inoculum(1). A 5-day theoretical BOD of 23.2% was observed for 1-dodecanol in a standard BOD dilution test using a mixed microbial inoculum(2-3). A 5-day theoretical BOD of 27-29.7% was observed for 1-dodecanol in a standard BOD aerobic screening test using a sewage inoculum or an acclimated activated sludge inoculum(4); using a Warburg respirometer technique and a sewage inoculum, a 6-hr theoretical BOD of 15.2% was observed(4). Using a Warburg respirometer technique and various activated sludge inoculum, respective 6-hr, 12-hr and 24-hr theoretical BODs of 4.5, 10.1 and 13.4% were observed(5). 1-Dodecanol was found to be readily biodegraded(6).
Bioaccumulative potential
An estimated BCF of 48 was calculated in fish for 1-dodecanol(SRC), using a log Kow of 5.13(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is moderate(SRC).
Mobility in soil
Koc values of 2042-3388 were reported for 1-dodecanol in humic acid(1). According to a classification scheme(2), this Koc range suggests that 1-dodecanol is expected to have slight mobility in soil. Koc values of 2570-6574, 2337-11,184, 7700 and 16,700-17,981 were reported for 1-dodecanol in activated sludge, sediment, suspended solids and suspended solids with activated sludge, respectively(1).
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: UN3077 (For reference only, please check.)
IMDG: UN3077 (For reference only, please check.)
IATA: UN3077 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
IATA: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 9 (For reference only, please check.)
IMDG: 9 (For reference only, please check.)
IATA: 9 (For reference only, please check.)
Packing group, if applicable
ADR/RID: III (For reference only, please check.)
IMDG: III (For reference only, please check.)
IATA: III (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Health effects of exposure to the substance have not been investigated adequately.
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.