Product name
Levofloxacin hemihydrate
CAS NO.
100986-85-4
M.F.
C18H20FN3O4
M.W
361.373
Structure
EINECS
600-146-0
Chemical Properties
Melting point
218 °C
Density
1.48g/cm3
Boiling point
571.5°Cat760mmHg
Flash point
299.4°C
Safety information
Package
Net weight
25kgs/drum
Gross weight
27.5kgs
Certificate
GMP, AFM, registration in Korea
Specification
Appearance
Light yellowish-white to yellow-white crystals or crystalline powder
Assay (on the anhydrous basis)
98.5-102.0%
Residue on ignition
NMT 0.2%
Heavy metals
NMT 10ppm
Organic impurities
N-Desmethyl levofloxacin NMT 0.3%
Diamine derivative NMT 0.3%
Levofloxacin N-oxide NMT 0.3%
9-Desfluoro levofloxacin NMT 0.3%
D-Isomer NMT 0.1%
Any unknown impurity
NMT 0.1%
Total impurities
NMT 0.5%
Optical rotation at 20 °C
-920~ -1060
Water
2.1% ~2.7%
Residual solvents
Chloroform
NMT 60ppm
Ethanol
NMT 1000ppm
DMSO
Usage
Antimicrobials
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