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阿哌沙班,Apixaban
  • 阿哌沙班,Apixaban
  • 阿哌沙班,Apixaban
  • 阿哌沙班,Apixaban

阿哌沙班,阿哌沙班原料藥,阿哌沙班工廠

價格 詢價
包裝 1kg
最小起訂量 1kg
發(fā)貨地 山東
更新日期 2024-08-01

產(chǎn)品詳情

中文名稱:阿哌沙班英文名稱:Apixaban
CAS:503612-47-3產(chǎn)地: 山東
保存條件: Refrigerator純度規(guī)格: 99.21%
產(chǎn)品類別: 醫(yī)藥原料藥
級別: 醫(yī)藥級別名: apaxaban,apixaban api,apixaban cas, cas 503612-47-3
分子式: C25H25N5O4用途: Cerebro-cardiovascular
外觀性狀: White powder
2024-08-01 阿哌沙班 Apixaban 1kg/RMB 山東 Refrigerator 99.21% 醫(yī)藥原料藥

Product name: Apixaban

Cas NO.: 503612-47-3

M.F: C25H25N5O4

M.W.: 459.5

Capacity: 200KG/M

Usage: Cerebro-cardiovascular

General: Apixaban is a potent, orally active, reversible, direct, and highly selective factor Xa active site inhibitor with antithrombotic activity. Apixaban inhibits free and thrombus-bound factor Xa and inhibits prothrombin activity. Apixaban has no direct effect on platelet aggregation, but indirectly inhibits thrombin-induced platelet aggregation. Through inhibition of factor Xa, apixaban inhibits thrombin generation and inhibits thrombus formation. The preclinical test results in animal models show that apixaban has antithrombotic effect at a dose level that does not affect the hemostatic function, and can prevent arterial and venous thrombosis. 

 

Product introduce: Apixaban is an anticoagulant used to prevent venous thromboembolism and atrial fibrillation stroke. It is a direct factor Xa inhibitor. Apixaban can be used for antithrombotic therapy in patients with acute coronary syndrome (ACS) and percutaneous coronary intervention (PCI) of atrial fibrillation. Clinical trials have confirmed the safety and effectiveness of Apixaban in patients with atrial fibrillation at the recommended dose. A new oral anticoagulant including Apixaban combined with P2Y12 inhibitor is currently recommended by North American guidance for preventing stroke and systemic embolism in patients with ACS or PCI with atrial fibrillation.

FunctionApixaban can prevent thrombin generation and thrombosis, and play an anticoagulant role by inhibiting coagulation factor Xa.

 

Origin: Apixaban has been listed in Europe since May 2011. The drug was developed by a joint venture between Pfizer and Bristol-Myers Squibb.

 

Drug efficacy: Apixaban is the third new oral anticoagulant listed after dabigatran and rivaroxaban. It has been approved in Europe to prevent venous thromboembolic events in patients undergoing elective hip or knee replacement surgery. The experimental results of these three oral anticoagulants show that rivaroxaban and apixaban stand out in the RECORD test and the ADVANCE test respectively. Experts say that rivaroxaban seems to have a slightly better effect, but the bleeding situation is more serious than that of apixaban. Experts attribute these differences to the time of administration. In the RECORD trial, rivaroxaban was administered 6-8 hours after operation, while in the ADVANCE trial, apixaban was administered 18 hours after operation. The closer the administration time of these drugs is to the operation, the better the curative effect, but the higher the risk of bleeding.


關(guān)鍵字: apixaban api;apaxaban;apixaban factory;apixaban cas;cas 503612-47-3;

公司簡介

濟(jì)南洣林藥業(yè)有限公司成立于2012年,是一家以創(chuàng)新為導(dǎo)向的現(xiàn)代制藥企業(yè)。洣林藥業(yè) 具有卓越的研發(fā)能力和完整的產(chǎn)業(yè)基地,具有國際質(zhì)量管理體系。致力于醫(yī)藥及高級醫(yī)藥中間體的研發(fā)、生產(chǎn)和定制。
成立日期 2012-04-12 (13年) 注冊資本 貳佰萬元整
員工人數(shù) 10-50人 年?duì)I業(yè)額 ¥ 500萬-1000萬
主營行業(yè) 醫(yī)藥中間體,合成材料中間體,原料藥,有機(jī)合成藥 經(jīng)營模式 貿(mào)易,工廠
  • 濟(jì)南洣林醫(yī)藥技術(shù)有限公司
非會員
  • 公司成立:13年
  • 注冊資本:貳佰萬元整
  • 企業(yè)類型:有限責(zé)任公司
  • 主營產(chǎn)品:阿哌沙班,阿哌沙班中間體,魯拉西酮,塞卡替尼
  • 公司地址:山東省濟(jì)南市高新區(qū)天辰路2177號聯(lián)合財(cái)富廣場1號樓2208室
詢盤

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