中文名稱: 伊立替康
中文同義詞: [1,4'-聯(lián)哌啶]-1'-羧酸(S)-4,11-二乙基-3,4,12,14-四氫-4羥基-3,14-二氧-1H-吡喃并[3',4':6,7]氮茚[1,2-B]喹啉-9-基酯;聯(lián)哌喜樹堿;(S)-4,11-二乙基-3,4,12,14-四氫-4-羥基-3,14-二氧代-1H-吡喃;伊立替康堿;(S)-4,11-二乙基-3,4,12,14-四氫-4-羥基-3,14-二氧代-1H-吡喃并[3',4':6,7]中氮茚并[1,2-B]喹啉-9-基 1,4'-聯(lián)哌啶-1'-羧酸酯;伊立替康三水鹽酸鹽;伊立替康(替康類);伊立替康(標(biāo)準(zhǔn)品)
英文名稱: Irinotecan
英文同義詞: Irinotecan (free Base);Irinotecan(TECANS);1,4'-Bipiperidine-1'-carboxylic acid (S)-4,11-diethyl-3,4,12,14- tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester;DQ-2805;(4S)-4,11-Diethyl-4-hydroxy-9-[[(4-piperidinopiperidino)carbonyl]oxy]-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione;SN-38-11;(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate;(4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl-[1,4'-bipiperidine]-1'-carboxylic acid
CAS號(hào): 97682-44-5
分子式: C33H39ClN4O6
分子量: 623.14
EINECS號(hào):
相關(guān)類別: TECANS替康類產(chǎn)品(Anti-cancer);Camptothecin series;喜樹堿系列;APIs;Natural Anti-cancer Medical Materials and It's Derivatives;API's;動(dòng)植物類抗腫瘤藥物;抗腫瘤藥;藥物;API;標(biāo)準(zhǔn)品;植物提取物;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Camptosar, Campto;Anti-cancer&immunity;醫(yī)藥中間體;喜樹堿的半合成衍生物;Anti cancer;Inhibitors;小分子抑制劑,天然產(chǎn)物;醫(yī)藥原料;醫(yī)藥原料藥;DNA損傷
化學(xué)性質(zhì) 淡黃色粉末,熔點(diǎn)222~223℃。
鹽酸伊立替康(Irinotecan Hydrochloride):C33H38N4O6?HCl?3H2O。[136572-09-3]。從水得極淡黃色針狀結(jié)晶或結(jié)晶性粉末,熔點(diǎn)256.5℃。[α]D20+67.7°(C=1,水)。UV吸收(乙醇):221,254,359,372nm(ε53800,36600,26200,25300)。2%水溶液的Ph值為4。急性毒性LD50小鼠(rng/kg):177.5腹腔注射,765.3口服。
用途 抗腫瘤藥。為DNA合成抑制劑。是喜樹堿的半合成衍生物。
用途 抗癌藥。
用途 抗腫瘤藥。為DNA合成抑制劑。是喜樹堿的半合成衍生物;用于制備鹽酸伊立替康和鹽酸伊立替康三水合物;抗癌藥。
Chinese name: irinotecan
(S) -4,11-diethyl-3,4,4,14-tetrahydro-4-hydroxy-3,14-di 2-B) quinolin-9-yl ester; bis (p) -pyridine; (S) -4,11-bis Ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyran; irinotecan; (S) -4,11-diethyl- 4-hydroxy-3,14-dioxo-1H-pyrano [3 ', 4': 6,7] azepeno [1,2-B] quinoline -li-yl 1,4'-bipiperidine-1'-carboxylate; irinotecan sulphate; irinotecan (piconet); irinotecan (standard)
English name: Irinotecan
1-carboxylic acid (S) -4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-4-ene- 3,14-dioxo-1H-pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinolin-9-yl ester; DQ-2805; (4S) -4,11-Diethyl- -hydroxy-9-[4-piperidinopiperidino carbonyl] oxy] -3,4,12,14-tetrahydro-1H-pyrano [3 ', 4': 6,7] indolizino [1,2-b] quinoline 17-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3, 13-diazapentacyclo [11.8.0.0 ^ {2, (21), 2,4 (9), 5,7,10,15 (20) -heptaen-7-yl 4 (2) 4-hydroxy-3,14-dioxo-1H-pyrano [3 ' , 4 ': 6,7] indolizino [1,2-b] quinolin-9-yl- [1,4'-bipiperidine] -1'-carboxylic acid
CAS Number: 97682-44-5
Molecular formula: C33H39ClN4O6
Molecular weight: 623.14
EINECS number:
Anti-cancer drugs; anti-cancer drugs; anti-cancer drugs; anti-cancer drugs; anti-cancer drugs; anti-cancer drugs; anti-cancer drugs; anti-cancer drugs; Order a copy of this thesis The pharmaceutical intermediates, the semi-synthetic derivatives of camptothecin, and the semi-synthetic derivatives of camptothecin, Anti-cancer; Inhibitors; small molecule inhibitors, natural products; pharmaceutical raw materials; pharmaceutical raw materials; DNA damage
Chemical properties of light yellow powder, the melting point of 222 ~ 223 ℃.
Irinotecan Hydrochloride: C33H38N4O6? HCl? 3H2O. [136572-09-3]. From the water was very light yellow needle crystal or crystalline powder, the melting point of 256.5 ℃. [α] D20 + 67.7 ° (C = 1, water). UV maximum absorption (ethanol): 221,254,359,372 nm (ε53800,36600,26200,25300). The Ph value of the 2% aqueous solution is 4. Acute Toxic LD50 Mice (rng / kg): 177.5 Intraperitoneal injection, 765.3 Oral.
Use Antitumor drugs. For DNA synthesis inhibitors. Is a semi-synthetic derivative of camptothecin.
Use anticancer drugs.
Use Antitumor drugs. For DNA synthesis inhibitors. Is a semi-synthetic derivative of camptothecin; for the preparation of irinotecan hydrochloride and irinotecan hydrochloride trihydrate; anti-cancer drugs.
抗寄生蟲類:硝唑尼特|甲硝唑|替硝唑|雙羥萘酸噻嘧啶|克洛索隆|鹽酸左旋咪唑
抗瘧疾類:磷酸氯喹|鹽酸阿莫地喹|磷酸哌喹|一鹽酸奎寧|奎寧|苯芴醇|硫酸奎寧
抗生素類:氯霉素|硫酸新霉素|環(huán)丙沙星|依托紅霉素|紅霉素|阿莫西林三水物|青霉素鉀|甲砜霉素|鹽酸四環(huán)素|阿奇 霉素|
頭孢拉定|羅紅霉素|霉酚酸|鹽酸環(huán)丙沙星|頭孢氨芐|阿洛西林鈉|妥布霉素|頭孢噻肟鈉|磷霉素鈉| 頭孢克洛|利
福昔明|頭孢西丁酸
泌尿系統(tǒng)類:甘露醇|呋塞米|氫氯噻嗪|鹽酸黃酮哌酯|磺胺甲惡唑|泛影酸鈉|琥珀酸索利那|加替沙星|非那雄胺
心腦血管類:阿魏酸乙酯|鹽酸倍他司汀|三磷酸腺苷二鈉|右旋鄰氯苯甘氨酸甲酯酒石酸鹽|鹽酸丁咯地爾|吡拉西坦| 長春胺|
鹽酸氟桂利嗪|鹽酸胺碘酮|阿魏酸鈉|鹽酸賽洛唑啉|硫酸氫氯吡格雷|奎尼丁|阿魏酸|鹽酸維拉 帕米|鹽酸普萘
洛爾|鹽酸萘甲唑啉|氨氯地平|鹽酸美西律|羥苯磺酸鈣|米屈肼|洛伐他汀|鹽酸妥拉唑林|
神經(jīng)系統(tǒng)類:甲磺酸雷沙吉蘭|普瑞巴林|卡馬西平|谷維素|托吡酯|鹽酸文拉法辛|丙戊酸鈉|鹽酸多塞平|加巴噴丁|非尼布特|
鹽酸度洛西汀|舒必利|巴氯芬|苯妥英鈉|馬來酸氟伏沙明|氫溴酸西酞普蘭
關(guān)鍵字: 伊立替康;伊立替康生產(chǎn)廠家;伊立替康廠家價(jià)格;伊立替康原藥廠家;伊立替康97682-44-5;伊立替康三水合物
長沙禎祥生物科技有限公司主營產(chǎn)品:甲磺酸雷沙吉蘭|普瑞巴林|卡馬西平|谷維素|托吡酯|鹽酸文拉法辛|丙戊酸鈉|鹽酸多塞平|加巴噴丁|非尼布特| 鹽酸度洛西汀|舒必利|巴氯芬|苯妥英鈉|馬來酸氟伏沙明|氫溴酸西酞普蘭 擁有按GMP標(biāo)準(zhǔn)建造從中 試到大生產(chǎn),設(shè)備先進(jìn),配套齊全的10000余平方米生產(chǎn)車間;擁有完善的質(zhì)量保證體系和健全質(zhì)量控制制度;擁有多套高壓 液相色譜儀,氣相色譜儀和紫外分光光度計(jì)等高效高靈敏度的分析儀器,對(duì)產(chǎn)品進(jìn)行有效的分析和監(jiān)控。公司已通過ISO9001 質(zhì)量體系認(rèn)證。