CD59產(chǎn)品信息
英文名稱:CD59 glycoprotein
中文名稱:CD59糖蛋白
靶點(diǎn)別稱:CD59
物種:Human
屬性:Protein
標(biāo)記:Biotin-labeled/Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(chǔ)(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
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CD59分子背景
CD59,也稱為膜攻擊復(fù)合物抑制因子(MACIF)、保護(hù)蛋白、1F5抗原、HRF-20和MIRL。CD59已被鑒定為一種糖基磷脂酰肌醇錨定的膜蛋白,作為膜攻擊復(fù)合物質(zhì)形成的抑制劑,調(diào)節(jié)補(bǔ)體激活。補(bǔ)體膜攻擊復(fù)合物(MAC)作用的強(qiáng)效抑制劑。通過與組裝MAC的C8和/或C9互補(bǔ)物結(jié)合起作用,從而防止完全形成滲透壓孔所需的C9多拷貝的摻入。這種抑制劑似乎具有物種特異性。參與與蛋白酪氨酸激酶復(fù)合的T細(xì)胞活化的信號(hào)轉(zhuǎn)導(dǎo)。
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關(guān)鍵字: CD59;CD59蛋白;CD59重組蛋白;ACRO;百普賽斯;
百普賽斯集團(tuán)ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國(guó)生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺(tái)型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團(tuán)業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國(guó)、美國(guó)、瑞士等12個(gè)城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計(jì)服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長(zhǎng)期、穩(wěn)定的合作伙伴關(guān)系。集團(tuán)旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。