Rabbit Anti-C4d-A Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:C4d-A
IR:Immunogen Range:1001-1100/1744
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:720
Swiss Prot:P0C0L4
Source:KLH conjugated synthetic peptide derived from human C4d-A:1001-1100/1744
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
Size:50ul
Concentration:1mg/ml
Applications:IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： C4d-A;complement C4-A prop;Acidic complement C4;Basic complement C4;CH;Chido blood group;CO4;CO4A_HUMAN;
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